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Protein Overview: NDST1_MOUSE

General Information:
Name(s) found: NDST1_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|90110380|sp|Q3UHN9.2|NDST1_MOUSE RecName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; AltName: Full=Glucosaminyl N-deacetylase/N-sulfotransferase 1; Short=NDST-1; AltName: Full=[Heparan sulfate]-glucosamine N-sulfotransferase [NCBI NR]
  • gi|50925370|gb|AAH79561.1| N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 [Mus musculus] [NCBI NR]
  • gi|4322251|gb|AAD15980.1| heparan sulfate N-deacetylase/N-sulfotransferase 1 [Mus musculus] [NCBI NR]
  • gi|42734444|ref|NP_032332.2| N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 [Mus musculus] [NCBI NR]
  • gi|41946076|gb|AAH66098.1| N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 [Mus musculus] [NCBI NR]
  • gi|148677871|gb|EDL09818.1| N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1, isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|148677870|gb|EDL09817.1| N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1, isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|148677869|gb|EDL09816.1| N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1, isoform CRA_a [Mus musculus] [NCBI NR]
  • Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 OS=Mus musculus GN=Ndst1 PE=1 SV=2 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):18-61054031 Heparan sulfate N-deacetylase/N-sulfotransferase 1 [hmr_yeast5_DM3-1_pombe.fasta]
  • N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; heparan sulfate-N-deacetylase/N-sulfotransferase; N-deacetylase/N-sulfotransferase-1; glucosaminyl N-deacetylase/N-sulfotransferase 1 [HMR_022704-rand.fasta]
  • N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 [Mus musculus]gi|50925370|gb|AAH79561.1| N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 [Mus musculus]gi|41946076|gb|AAH66098.1| N-deacetylase/N-sulfotransferase (heparan glucosaminyl) [nrdb_11152004_Chlamydomonas]
  • N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST-1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N-heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • heparan sulfate N-deacetylase/N-sulfotransferase 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Ndst1 Isoform 1 of Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Ndst1 Isoform 1 of Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 ENSMUSG00000054008 IPI00404189 IPI00742333 IPI00742324 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00404189.3|SWISS-PROT:Q3UHN9-1|ENSEMBL:ENSMUSP00000068687|REFSEQ:NP_032332 Tax_Id=10090 Gene_Symbol=Ndst1 Isoform 1 of Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 [ipi.MOUSE.fasta.20090209]
  • Isoform 1 of Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 OS=Mus musculus GN=Ndst1 [011711_HMR.fasta]
  • sp|Q3UHN9|NDST1_MOUSE Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 OS=Mus musculus GN=Ndst1 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 882 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    Golgi apparatus [IEA]
    Biological Process: embryonic development [IGI]
    embryonic neurocranium morphogenesis [IMP]
    smoothened signaling pathway [IGI]
    protein amino acid deacetylation [TAS]
    fibroblast growth factor receptor signaling pathway [IMP]
    respiratory gaseous exchange [IMP]
    protein amino acid sulfation [IMP][TAS]
    organ morphogenesis [IMP]
    embryonic viscerocranium morphogenesis [IMP]
    MAPKKK cascade [IMP]
    inflammatory response [IEA]
    midbrain development [IGI]
    forebrain development [IGI][IMP]
    polysaccharide biosynthetic process [IMP]
    glycosaminoglycan metabolic process [IMP]
    Molecular Function: [heparan sulfate]-glucosamine N-sulfotransferase activity [TAS]
    catalytic activity [IEA]
    sulfotransferase activity [IEA]
    transferase activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPALACLRRL CRHLSPQAVL FLLFVFCLFS VFVSAYYLYG WNRGLEPSAD ASESDCGDPP  60
   61 PVAPSRLLPI KPVQAVAPSR TDPLVLVFVE SLYSQLGQEV VAILESSRFK YRTEIAPGKG 120
  121 DMPTLTDKGR GRFALIIYEN ILKYVNLDAW NRELLDKYCV AYGVGIIGFF KANENSLLSA 180
  181 QLKGFPLFLH SNLGLKDCSI NPKSPLLYVT RPSEVEKGVL PGEDWTVFQS NHSTYEPVLL 240
  241 AKTRSSESIP HLGADAGLHA ALHATVVQDL GLHDGIQRVL FGNNLNFWLH KLVFVDAVAF 300
  301 LTGKRLSLPL DRYILVDIDD IFVGKEGTRM KVEDVKALFD TQNELRTHIP NFTFNLGYSG 360
  361 KFFHTGTDAE DAGDDLLLSY VKEFWWFPHM WSHMQPHLFH NQSVLAEQMA LNKKFAVEHG 420
  421 IPTDMGYAVA PHHSGVYPVH VQLYEAWKQV WGIRVTSTEE YPHLKPARYR RGFIHNGIMV 480
  481 LPRQTCGLFT HTIFYNEYPG GSSELDKIIN GGELFLTVLL NPISIFMTHL SNYGNDRLGL 540
  541 YTFKHLVRFL HSWTNLRLQT LPPVQLAQKY FQIFSEEKDP LWQDPCEDKR HKDIWSKEKT 600
  601 CDRFPKLLII GPQKTGTTAL YLFLGMHPDL SSNYPSSETF EEIQFFNGHN YHKGIDWYME 660
  661 FFPIPSNTTS DFYFEKSANY FDSEVAPRRA AALLPKAKIL SILINPADRA YSWYQHQRAH 720
  721 DDPVALKYTF HEVITAGPDA SSKLRALQNR CLVPGWYATH IERWLSAFHA NQILVLDGKL 780
  781 LRTEPAKVMD TVQKFLGVTS TVDYHKTLAF DPKKGFWCQL LEGGKTKCLG KSKGRKYPEM 840
  841 DLDSRAFLKD YFRDHNIELS KLLYKMGQTL PTWLREDLQN TR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle