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Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate. Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate. Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-desulfoheparin = adenosine 3',5'-bisphosphate + heparin.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: [heparan sulfate]-glucosamine N-sulfotransferase activity
Acc: GO:0015016
Aspect: Molecular Function
Desc: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-desulfoheparin = adenosine 3',5'-bisphosphate + heparin.
Synonyms:
  • glucosaminyl N-deacetylase/N-sulfotransferase activity
  • heparan sulfate N-sulfotransferase activity
  • PAPS:DSH sulfotransferase activity
  • GO:0015022
  • 3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity
  • GO:0004393
  • N-HSST activity
  • heparin N-sulfotransferase activity
  • N-heparan sulfate sulfotransferase activity
  • heparan sulfate 2-N-sulfotransferase activity
  • 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity
  • PAPS:N-desulfoheparin sulfotransferase activity
  • N-desulfoheparin sulfotransferase activity
  • heparin N-deacetylase/N-sulfotransferase activity
  • desulfoheparin sulfotransferase activity
  • 3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity
  • heparan sulfate N-deacetylase/N-sulfotransferase activity
  • heparin N-deacetylase/N-sulphotransferase activity
  • 3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity
  • heparin-glucosamine N-sulfotransferase activity
  • [heparan sulphate]-glucosamine N-sulphotransferase activity
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015016 - [heparan sulfate]-glucosamine N-sulfotransferase activity (interactive image map)

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