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Protein Overview: UB2E2_MOUSE

General Information:
Name(s) found: UB2E2_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|47716680|sp|Q91W82.1|UB2E2_MOUSE RecName: Full=Ubiquitin-conjugating enzyme E2 E2; AltName: Full=Ubiquitin-protein ligase E2; AltName: Full=Ubiquitin carrier protein E2 [NCBI NR]
  • gi|21450233|ref|NP_659088.1| ubiquitin-conjugating enzyme E2E 2 [Mus musculus] [NCBI NR]
  • gi|16740795|gb|AAH16265.1| Ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) [Mus musculus] [NCBI NR]
  • gi|148688709|gb|EDL20656.1| ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast), isoform CRA_a [Mus musculus] [NCBI NR]
  • (Q91W82) Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2) [Swiss-Prot]
  • Ubiquitin-conjugating enzyme E2 E2 OS=Mus musculus GN=Ube2e2 PE=2 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):None Similar to ubiquitin-conjugating enzyme E2E 3 [hmr_yeast5_DM3-1_pombe.fasta]
  • cDNA sequence BC016265 [HMR_022704-rand.fasta]
  • ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast); cDNA sequence BC016265; TBC1 domain family, member 12 [071204_hmrz_cont.fasta]
  • Ubiquitin-conjugating enzyme E2 E2 [ipi.MOUSE.v3.06.fasta]
  • ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) [Mus musculus]gi|16740795|gb|AAH16265.1| Ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) [Mus musculus]gi|47716680|sp|Q91W82|UB6B_MOUSE Ubiquitin-conjugating enzyme E2 E2 (Ubiquitin-p [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Ubiquitin-conjugating enzyme E2 E2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_144839) hypothetical protein MGC28917 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Ubiquitin-conjugating enzyme E2 E2 (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast), isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 UBIQUITIN-CONJUGATING ENZYME E2 E2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Ube2e2 Ubiquitin-conjugating enzyme E2 E2 [mouse-ipi-250309-contam.fasta]
  • ubiquitin-conjugating enzyme E2E 2 [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Ube2e2 Ubiquitin-conjugating enzyme E2 E2 ENSMUSG00000058317 IPI00127440 IPI00881871 IPI00881770 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • ubiquitin-conjugating enzyme E2 E2 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00127440.1|SWISS-PROT:Q91W82|ENSEMBL:ENSMUSP00000075495|REFSEQ:NP_659088|VEGA:OTTMUSP00000034861 Tax_Id=10090 Gene_Symbol=Ube2e2 Ubiquitin-conjugating enzyme E2 E2 [ipi.MOUSE.fasta.20090209]
  • Ubiquitin-conjugating enzyme E2 E2 OS=Mus musculus GN=Ube2e2 [011711_HMR.fasta]
  • sp|Q91W82|UB2E2_MOUSE Ubiquitin-conjugating enzyme E2 E2 OS=Mus musculus GN=Ube2e2 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 201 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTEAQRVDD SPSTSGGSSD GDQRESVQQE PDREQVQPKK KEGKISSKTA AKLSTSAKRI  60
   61 QKELAEITLD PPPNCSAGPK GDNIYEWRST ILGPPGSVYE GGVFFLDITF SPDYPFKPPK 120
  121 VTFRTRIYHC NINSQGVICL DILKDNWSPA LTISKVLLSI CSLLTDCNPA DPLVGSIATQ 180
  181 YMTNRAEHDR MARQWTKRYA T

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..201] PSI-BLAST 50.522879 Human ubiquitin conjugating enzyme E2E2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  11.3486134076304 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  11.2964721480824 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  10.2401422444624 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  8.93602533934698 bayes_pls_golite062009
  • ligase activity
    		•  5.17219147802758 bayes_pls_golite062009
  • SUMO ligase activity
    		•  3.88357560284404 bayes_pls_golite062009
  • ISG15 ligase activity
    		•  3.37361650623694 bayes_pls_golite062009
  • HLH domain binding
    		•  2.41376652679018 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.21355731489173 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.13970605403492 bayes_pls_golite062009
  • DNA binding
    		•  1.95596447916631 bayes_pls_golite062009
  • protein binding
    		•  1.77678273247394 bayes_pls_golite062009
  • binding
    		•  1.75350658654805 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.5236035191291 bayes_pls_golite062009
  • transcription activator activity
    		•  1.19240180311941 bayes_pls_golite062009
  • catalytic activity
    		•  0.891402822028799 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  0.715654744941217 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.58835335751383 bayes_pls_golite062009
  • kinase activity
    		•  0.519703305315987 bayes_pls_golite062009
  • protein kinase activity
    		•  0.443948654247666 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.373779304908933 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.182854082413338 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.122859425935324 bayes_pls_golite062009
  • transferase activity
    		•  0.0984525836903841 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0104967529560147 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle