Protein Overview: JARD2_MOUSE

General Information:
Name(s) found:	JARD2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|780144\|dbj\|BAA06736.1\| jumonji protein [Mus musculus] [NCBI NR] pir\|\|T30254 jumonji protein - mouse [NCBI NR] gi\|38173749\|gb\|AAH60695.1\| Jumonji, AT rich interactive domain 2 [Mus musculus] [NCBI NR] gi\|30851587\|gb\|AAH52444.1\| Jumonji, AT rich interactive domain 2 [Mus musculus] [NCBI NR] gi\|26337159\|dbj\|BAC32264.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|2498495\|sp\|Q62315.1\|JARD2_MOUSE RecName: Full=Protein Jumonji; AltName: Full=Jumonji/ARID domain-containing protein 2 [NCBI NR] gi\|11230774\|ref\|NP_068678.1\| jumonji protein [Mus musculus] [NCBI NR] (Q62315) Jumonji protein (Jumonji/ARID domain-containing protein 2) [Swiss-Prot] Protein Jumonji OS=Mus musculus GN=Jarid2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):13-44310327 Jumonji protein [hmr_yeast5_DM3-1_pombe.fasta] jumonji protein [HMR_022704-rand.fasta] Jumonji protein [ipi.MOUSE.v3.06.fasta] jumonji protein [Mus musculus]gi\|38173749\|gb\|AAH60695.1\| Jumonji protein [Mus musculus]gi\|30851587\|gb\|AAH52444.1\| Jumonji protein [Mus musculus]gi\|780144\|dbj\|BAA06736.1\| jumonji protein [Mus musculus]gi\|7513702\|pir\|\|T30254 jumonji protein - mousegi\|2 [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Jumonji protein [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_021878) jumonji protein [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] jumonji protein [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Protein Jumonji (Jumonji/ARID domain-containing protein 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Jumonji, AT rich interactive domain 2 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 JUMONJI PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Jarid2 Protein Jumonji [mouse-ipi-250309-contam.fasta] Jumonji protein (Jumonji/ARID domain-containing protein 2) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Jarid2 Protein Jumonji ENSMUSG00000038518 IPI00124575 [IPIxENS.MOUSE_plus_REVERSE.fasta] protein Jumonji [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00124575.1\|SWISS-PROT:Q62315\|TREMBL:Q1LZL9;Q3TPU4;Q3UHS7\|ENSEMBL:ENSMUSP00000037774\|REFSEQ:NP_068678 Tax_Id=10090 Gene_Symbol=Jarid2 Protein Jumonji [ipi.MOUSE.fasta.20090209] jumonji, AT rich interactive domain 2 [Mus musculus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform 1 of Protein Jumonji OS=Mus musculus GN=Jarid2 [011711_HMR.fasta] Tax_Id=10090 Gene_Symbol=Jarid2 Isoform 1 of Protein Jumonji [EBI-IPI_mouse_2_08-18-2011_reversed.fasta] sp\|Q62315\|JARD2_MOUSE Protein Jumonji OS=Mus musculus GN=Jarid2 PE=1 SV=1 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	1234 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] histone methyltransferase complex [IDA] ESC/E(Z) complex [IDA] intracellular [IEA]
Biological Process:	chromatin modification [IEA] negative regulation of histone methylation [IDA] transcription [IEA] multicellular organismal development [IEA] negative regulation of cell proliferation [IMP] spleen development [IMP] regulation of transcription [IEA] regulation of cell proliferation [IMP] thymus development [IMP] negative regulation of transcription from RNA polymerase II promoter [IGI] positive regulation of histone H3-K9 methylation [IDA] negative regulation of transcription, DNA-dependent [IDA] stem cell differentiation [IMP] liver development [IMP] cell differentiation [IEA]
Molecular Function:	DNA binding [IDA][TAS] protein binding [IPI] [NOT]histone demethylase activity [IDA] chromatin binding [IDA] transcription repressor activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKERPKRNI IQKKYDDSDG IPWSEERVVR KVLYLSLKEF KNAQKRQHGE GLAGSLKAVN  60
   61 GLLGNAQAKA LGPASEQSEN EKDDASQVSS TSNDVSSSDF EEGPSRKRPR LQAQRKFAQS 120
  121 QPNSPSTTPV KIVEPLLPPP ATQISDLSKR KPKTEDFLTF LCLRGSPALP NSMVYFGSSQ 180
  181 DEEDVEEEDD ETEDVKATTN NASSSCQSTP RKGKTHKHVH NGHVFNGSSR SAREKEPAHK 240
  241 HRSKEATPGK EKHSEPRADS RREQASGAQP TAASAAASSA KGLAANHQPP PSHRSAQDLR 300
  301 KQVSKVNGVT RMSSLGAGTN SAKKIREVRP SPSKTVKYTA TVTKGTVTYT KAKRELVKET 360
  361 KPNHHKPSSA VNHTISGKTE SSNAKTRKQV LSLGGASKST GPAASGLKAS SRLNPKSCTK 420
  421 EVGGRQLREG LRNSKRRLEE AQQVDKPQSP PKKMKGVAGN AEAPGKKASA ASGEKSLLNG 480
  481 HVKKEVPERS LERNRPKRAA AGKNMLGKQA HGKTEGTPCE NRSTSQPESS HKPHDPQGKP 540
  541 EKGSGKSGWA AMDEIPVLRP SAKEFHDPLI YIESVRAQVE KYGMCRVIPP PDWRPECKLN 600
  601 DEMRFVTQIQ HIHKLGRRWG PNVQRLACIK KHLRSQGITM DELPLIGGCE LDLACFFRLI 660
  661 NEMGGMQQVT DLKKWNKLAD MLRIPKTAQD RLAKLQEAYC QYLLSYDSLS PEEHRRLEKE 720
  721 VLMEKEILEK RKGPLEGHTE SDHHKFHSLP RFEPKNGLVH GVTPRNGFRS KLKEVGRAPL 780
  781 KTGRRRLFAQ EKEVVKEEEE DKGVLNDFHK CIYKGRSVSL TTFYRTARNI MNMCFSKEPA 840
  841 PAEIEQEYWR LVEEKDCHVA VHCGKVDTNT HGSGFPVGKS EPFSRHGWNL TVLPNNTGSI 900
  901 LRHLGAVPGV TIPWLNIGMV FSTSCWSRDQ NHLPYIDYLH TGADCIWYCI PAEEENKLED 960
  961 VVHTLLQGNG TPGLQMLESN VMISPEVLCK KGIKVHRTVQ QSGQFVVCFP GSFVSKVCCG1020
 1021 YNVSETVHFA TTQWTSMGFE TAKEMKRRHI AKPFSMEKLL YQIAQAEAKK ENGPTLSTIS1080
 1081 ALLDELRDTE LRQRRLLFEA GLHSSARYGS HDGNSTVADG KKKPRKWLQL ETSERRCQIC1140
 1141 QHLCYLSMVV QENENVVFCL ECALRHVEKQ KSCRGLKLMY RYDEEQIISL VNQICGKVSG1200
 1201 KHGGIENCLN KPTPKRGPRK RATVDVPPSR LPSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: JARD2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: