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Protein Overview: gi|3327040

General Information:
Name(s) found: gi|3327040 [NCBI NR]
Description(s) found:
Found 5 descriptions.
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  • gi|3327040|dbj|BAA31588.1| KIAA0613 protein [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 734 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAADSTSMSY SVTLTGPGPW GFRLQGGKDF NMPLTISRIT PGSKAAQSQL SQGDLVVAID  60
   61 GVNTDTMTHL EAQNKIKSAS YNLSLTLQKS KRPIPISTTA PPVQTPLPVI PHQKDPALDT 120
  121 NGSLVAPSPS PEARASPGTP GTPELRPTFS PAFSRPSAFS SLAEASDPGP PRASLRAKTS 180
  181 PEGARDLLGP KALPGSSQPR QYNNPIGLYS AETLREMAQM YQMSLRGKAS GVGLPGGSLP 240
  241 IKDLAVDSAS PVYQAVIKSQ NKPEDEADEW ARRSSNLQSR SFRILAQMTG TEFMQDPDEE 300
  301 ALRRSSTPIE HAPVCTSQAT TPLLPASAQP PAAASPSAAS PPLATAAAHT AIASASTTAP 360
  361 ASSPADSPRP QASSYSPAVA ASSAPATHTS YSEGPAAPAP KPRVVTTASI RPSVYQPVPA 420
  421 STYSPSPGAN YSPTPYTPSP APAYTPSPAP AYTPSPVPTY TPSPAPAYTP SPAPNYNPAP 480
  481 SVAYSGGPAE PASRPPWVTD DSFSQKFAPG KSTTSISKQT LPRGGPAYTP AGPQVPPLAR 540
  541 GTVQRAERFP ASSRTPLCGH CNNVIRGPFL VAMGRSWHPE EFTCAYCKTS LADVCFVEEQ 600
  601 NNVYCERCYE QFFAPLCAKC NTKIMGEVMH ALRQTWHTTC FVCAACKKPF GNSLFHMEDG 660
  661 EPYCEKDYIN LFSTKCHGCD FPVEAGDKFI EALGHTWHDT CFICAVCHVN LEGQPFYSKK 720
  721 DRPLCKKHAH TINL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] PSI-BLAST 12.221849 Solution Structure of ZASP's PDZ domain
    2 View Details [70..157] deduced N/A No confident structure predictions are available.
    3 View Details [158..241] deduced N/A No confident structure predictions are available.
    4 View Details [242..299] deduced N/A No confident structure predictions are available.
    5 View Details [300..414] deduced N/A No confident structure predictions are available.
    6 View Details [415..491] FFAS03 1.14 Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP
    7 View Details [492..550] PSI-BLAST 7.69897 Transcription factor IIIA, TFIIIA
    8 View Details [551..734] PSI-BLAST 32.522879 No description for 2i13A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  3.60106431937699 bayes_pls_golite062009
  • structural constituent of muscle
    		•  3.0482783169186 bayes_pls_golite062009
  • actinin binding
    		•  2.91261541242779 bayes_pls_golite062009
  • binding
    		•  2.6316969452405 bayes_pls_golite062009
  • protein binding
    		•  2.25893018754605 bayes_pls_golite062009
  • actin binding
    		•  2.13642404399707 bayes_pls_golite062009
  • transporter activity
    		•  0.782216866213126 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.699604120098573 bayes_pls_golite062009
  • PDZ domain binding
    		•  0.53069705861477 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.434921764966531 bayes_pls_golite062009
  • actin filament binding
    		•  0.395248867755308 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.250590541549843 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.182094987832726 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.15766709142367 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • transporter activity
    		•  2.52497552014278 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.40658013079084 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.39214016658615 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.35708720741144 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.28572270826306 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.2679790267601 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.26439443616623 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.08046022919779 bayes_pls_golite062009
  • motor activity
    		•  2.07772440476994 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.07687836248701 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.03985463174903 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.03554410262972 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.03501965794966 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.96755553127373 bayes_pls_golite062009
  • binding
    		•  1.95375255800529 bayes_pls_golite062009
  • ATPase activity
    		•  1.90719478261095 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.89951058094584 bayes_pls_golite062009
  • actin binding
    		•  1.73490290591968 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.48825800569252 bayes_pls_golite062009
  • structural constituent of muscle
    		•  1.35085869260647 bayes_pls_golite062009
  • microtubule motor activity
    		•  1.27318173398333 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.17138261833001 bayes_pls_golite062009
  • hydrolase activity
    		•  1.00498978255976 bayes_pls_golite062009
  • tubulin binding
    		•  0.820284115671881 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.789128756960111 bayes_pls_golite062009
  • actin filament binding
    		•  0.68421152762816 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.637621825415179 bayes_pls_golite062009
  • microtubule binding
    		•  0.634383883834603 bayes_pls_golite062009
  • GTPase activity
    		•  0.603004420222648 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.509855138537351 bayes_pls_golite062009
  • nucleotide binding
    		•  0.503649548307811 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.49583023878914 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.495817032502758 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.249266001065856 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.16639805763162 bayes_pls_golite062009
  • GTP binding
    		•  0.163692554293628 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.160665710980295 bayes_pls_golite062009
  • protein binding
    		•  0.102043618157662 bayes_pls_golite062009
  • protein transporter activity
    		•  0.0840319419284095 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0197193998031486 bayes_pls_golite062009
  • ATP binding
    		•  0.00203463095479706 bayes_pls_golite062009
    7
    Term Confidence Notes
  • binding
    		•  2.47962305876847 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.22104591928521 bayes_pls_golite062009
  • DNA binding
    		•  2.00908648793732 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.98196470793823 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.92901308597163 bayes_pls_golite062009
  • transcription factor activity
    		•  1.10908190809074 bayes_pls_golite062009
  • protein binding
    		•  0.905022998164426 bayes_pls_golite062009
  • tubulin binding
    		•  0.744315484113484 bayes_pls_golite062009
  • microtubule binding
    		•  0.576452165256057 bayes_pls_golite062009
  • chromatin binding
    		•  0.44494725351897 bayes_pls_golite062009
  • transcription activator activity
    		•  0.28378358922747 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.27673489856581 bayes_pls_golite062009
  • signal transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle