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Protein Overview: gi|109462223

General Information:
Name(s) found: gi|109462223 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|109462223|ref|XP_001066539.1| PREDICTED: similar to Bloom syndrome protein homolog [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 1401 amino acids

    Gene Ontology:
    Cellular Component: replication fork [UNKNOWN]
    chromosome, telomeric region [UNKNOWN]
    nucleus [UNKNOWN][IEA]
    PML body [UNKNOWN]
    cytoplasm [UNKNOWN]
    pronucleus [UNKNOWN]
    lateral element [UNKNOWN]
    nuclear matrix [UNKNOWN]
    nucleolus [UNKNOWN]
    cellular_component [ND]
    intracellular [IEA]
    male germ cell nucleus [UNKNOWN]
    Biological Process: DNA repair [UNKNOWN][IEA]
    biological_process [ND]
    response to X-ray [UNKNOWN]
    DNA replication [IEA]
    DNA recombination [IEA]
    telomere maintenance [UNKNOWN]
    positive regulation of transcription [UNKNOWN]
    negative regulation of mitotic recombination [UNKNOWN]
    alpha-beta T cell differentiation [UNKNOWN]
    response to DNA damage stimulus [UNKNOWN]
    cellular metabolic process [IEA]
    regulation of cyclin-dependent protein kinase activity [UNKNOWN]
    negative regulation of DNA recombination [UNKNOWN]
    positive regulation of alpha-beta T cell proliferation [UNKNOWN]
    chromosome organization [UNKNOWN]
    negative regulation of cell division [UNKNOWN]
    regulation of binding [UNKNOWN]
    replication fork processing [UNKNOWN]
    protein oligomerization [UNKNOWN]
    Molecular Function: ATPase activity [UNKNOWN]
    DNA strand annealing activity [UNKNOWN]
    bubble DNA binding [UNKNOWN]
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [IEA]
    ATP-dependent helicase activity [UNKNOWN][IEA]
    helicase activity [UNKNOWN][IEA]
    four-way junction helicase activity [UNKNOWN]
    ATP-dependent DNA helicase activity [UNKNOWN]
    molecular_function [ND]
    single-stranded DNA binding [UNKNOWN]
    nucleotide binding [IEA]
    DNA binding [IEA]
    ATP binding [UNKNOWN][IEA]
    p53 binding [UNKNOWN]
    protein binding [UNKNOWN]
    G-quadruplex DNA binding [UNKNOWN]
    catalytic activity [IEA]
    ATP-dependent 3'-5' DNA helicase activity [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAVPLNNLQ EQLQRHSARK LKNQFSVSKP KPSGFTFKKK TPEGDVSVVR TPVLSDKDVN  60
   61 MSEALSYTEP PLHKPKQQSN IDGFFKNSPG GQQSKETCSE LSLPEVVQIP QDASCTTPKT 120
  121 PAVKKPHVAI FKKLEFSSSA DSLSDWADID DFDVPASDAF VSLTRNPTTR VSTAKKLSSS 180
  181 KRNFFKPPPR ASAVKADLTP SSPECLQVDL TKEQEEEADC LSRDVICIDT DPASEELLEK 240
  241 DVQEGLSLDA RLGTERVDSA KKSHEDEAAF QSPQNALYFE HNDNDYDIDF VPPSPEEIIS 300
  301 TASSSLKCSS MLKDLDDSDK EKDILSTSKD LSKPEEMTTP KSDLGTNEDC DAQQTSLQQQ 360
  361 LIRVMEHICK LVDTVPIDEL KALTCGDKLL QQRDIRRKLL AEAGFNRNDV NLLGSLWRHR 420
  421 PDSLDNTVQC DSCPVGHPGK ELNSPYLPSH SLSTEECLPT TASGKTGFSA TPKSLSERPP 480
  481 LNSHLQKSFV SSNWAETPRT ESRTESTYFP GSVLTSTTVK DESKHVASGR DIEREVQASY 540
  541 DIDNFNIDDF DDDDDDDWEN IMHNFSVSKS STAAYPPIKE GGPVKSLSER ISSAKAKFLP 600
  601 VASTAQNKNL SESIQNCSDK FAQNLSSKNP KHEHFQSLNF PHTKEMMKIF RKKFGLHNFR 660
  661 TNQLEAINAA LLGEDCFILM PTGGGKSLCY QLPACVSPGV TIVISPLRSL IVDQVQKLTS 720
  721 FDIPATYLTG DKTDSEAANI YLQLSKKDPI IKLLYVTPEK VCASNRLIST LENLYERKLL 780
  781 ARFVIDEAHC VSQWGHDFRQ DYKRMNMLRQ RFPSVPVMAL TATANPRVQK DILTQLKILR 840
  841 PQVFSMSFNR HNLKYYVLPK KPKKVALDCL EWIRKHHPYD SGIIYCLSRK ECDTMADTLQ 900
  901 REGLAALAYH AGLSDSARDE VQHKWINQDN CQVICATIAF GMGIDKPDVR FVVHASLPKS 960
  961 VEGYYQESGR AGRDGEISHC VLFYTYHDVT RLKRLIMMEK DGNYHTRETH VNNLYSMVHY1020
 1021 CENITECRRI QLLAYFGEKG FNPDFCKKHP DVSCDNCCKT KDYKTKDVTD DVKNIVRFVQ1080
 1081 EHSSSPGTRN IGPAGRFTLN MLVDIFLGSK SAKVQSGIFG KGSAYSRHNA ERLFKKLILD1140
 1141 KILDEDLYIN ANDQPIAYVM LGTKAHSVLS GHLKVDFMET ENSSSVKKQK AAVAHVSQRD1200
 1201 EAVMKCLGEL ADVCKLLGKV FGVHYFNIFN TATLKKLAES LSSDPEVLLQ IDGVTEDKLE1260
 1261 KYGAEIIPVL QKYAEWTLPA EGGSPGSRGS RRSTPEETEE EEAVSSHYFA NQTRNERKRK1320
 1321 KVSASQKPKR RRTSYGGGFR AKGGSTTCRK PSSKSKFSGV TGSRSASCAS QATSAASRKL1380
 1381 GIMAPPKPVN RPFLRPAYAF S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle