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Protein Overview: ATOX1

General Information:
Name(s) found: ATOX1 [HGNC (HUGO)]
Description(s) found:
Found 59 descriptions.
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  • ATX1 antioxidant protein 1 homolog (yeast) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 68 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK  60
   61 TVSYLGLE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. ATOX1 gi|112491310 gi|13786858 gi|14277752, gi|... gi|150261449 gi|219109210, gi... gi|3659984 gi|56554577 gi|56966260, gi|...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] PSI-BLAST 14.69897 ATX1 metallochaperone protein (ATOX1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • copper chaperone activity
    		•  6.14761367748172 bayes_pls_golite062009
  • metallochaperone activity
    		•  5.42894566783157 bayes_pls_golite062009
  • copper ion binding
    		•  5.32798570870322 bayes_pls_golite062009
  • copper-dependent protein binding
    		•  4.95395467138629 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  4.35398003989182 bayes_pls_golite062009
  • copper-exporting ATPase activity
    		•  4.01340421656566 bayes_pls_golite062009
  • copper-transporting ATPase activity
    		•  3.98014937932947 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  3.67313485213724 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  3.36143792136115 bayes_pls_golite062009
  • superoxide dismutase copper chaperone activity
    		•  3.23752773949358 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.07976644601593 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.00431429991351 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  2.81498319767782 bayes_pls_golite062009
  • metal ion binding
    		•  2.69806984896689 bayes_pls_golite062009
  • cation binding
    		•  2.69806984896689 bayes_pls_golite062009
  • ion binding
    		•  2.69078950610234 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.64028711724976 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.63703148987083 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
    		•  2.38802353099961 bayes_pls_golite062009
  • transition metal ion binding
    		•  2.33752521414572 bayes_pls_golite062009
  • binding
    		•  2.10099654348697 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.89914790023437 bayes_pls_golite062009
  • transporter activity
    		•  1.18017764841747 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.01970137875178 bayes_pls_golite062009
  • protein binding
    		•  0.889287086236279 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.841996187774093 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.508360443861132 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.470327716716451 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.452477805627897 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.45132236262635 bayes_pls_golite062009
  • ATPase activity
    		•  0.392266185712579 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle