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Protein Overview: gi|158257714, gi...

General Information:
Name(s) found: gi|158257714 [NCBI NR]
gi|14141166 [NCBI NR]
gi|12654635 [NCBI NR]
gi|119617113 [NCBI NR]
Description(s) found:
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  • gi|158257714|dbj|BAF84830.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|14141166|ref|NP_114366.1| poly(rC) binding protein 2 isoform b [Homo sapiens] [NCBI NR]
  • gi|12654635|gb|AAH01155.1| Poly(rC) binding protein 2 [Homo sapiens] [NCBI NR]
  • gi|119617113|gb|EAW96707.1| poly(rC) binding protein 2, isoform CRA_b [Homo sapiens] [NCBI NR]
  • poly(rC)-binding protein 2 isoform b [hmr_yeast5_DM3-1_pombe.fasta]
  • poly(rC)-binding protein 2 isoform b; poly(rC)-binding protein 2; alpha-CP2; heterogenous nuclear ribonucleoprotein E2 [HMR_022704.fasta]
  • poly(rC)-binding protein 2 isoform b; alpha-CP2; poly(rC)-binding protein 2; heterogenous nuclear ribonucleoprotein E2 [Human2242005.fasta]
  • poly(rC)-binding protein 2 isoform b [Homo sapiens]gi|50925529|gb|AAH78909.1| Unknown (protein for MGC:93668) [Rattus norvegicus]gi|12654635|gb|AAH01155.1| Poly(rC)-binding protein 2, isoform b [Homo sapiens]gi|2500577|sp|Q61990|PCB2_MOUSE Poly(rC)-bin [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 poly(rC)-binding protein 2 isoform b [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_031989) poly(rC)-binding protein 2, isoform b; alpha-CP2; poly(rC)-binding protein 2; heterogenous nuclear ribonucleoprotein E2 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • poly(rC)-binding protein 2 isoform b [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Poly(rC)-binding Protein 2 isoform b [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Tax_Id=9606 Poly(rC)-binding Protein 2 isoform b [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • poly(rC)-binding protein 2 isoform b; alpha-CP2; poly(rC)-binding protein 2; heterogenous nuclear ribonucleoprotein E2 [Homo sapiens] [HumanGallus06162005.fasta]
  • poly(rC)-binding protein 2 isoform b; poly(rC)-binding protein 2; alpha-CP2; heterogenous nuclear ribonucleoprotein E2 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • poly(rC) binding protein 2 isoform b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • poly(rC) binding protein 2, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Poly(rC) binding protein 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 POLY(RC)-BINDING PROTEIN 2, ISOFORM B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PCBP2 poly(rC) binding protein 2 isoform b [human-ipi-250309-contam.fasta]
  • IPI:IPI00012066.2|TREMBL:A8K7X6|ENSEMBL:ENSP00000352228|REFSEQ:NP_114366|VEGA:OTTHUMP00000167699 Tax_Id=9606 Gene_Symbol=PCBP2 poly(rC) binding protein 2 isoform b [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=PCBP2 poly(rC)-binding protein 2 isoform b [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Poly(RC) binding protein 2, isoform CRA_b OS=Homo sapiens GN=PCBP2 [011711_HMR.fasta]
  • Poly(RC) binding protein 2, isoform CRA_b OS=Homo sapiens GN=PCBP2 PE=2 SV=1 [UniProt_Human_05-17-2011_reversed.fasta]
  • GeneSymbol=PCBP2 Synonyms=HNRPE2|MGC110998|hnRNP-E2 poly(rC)-binding protein 2 isoform b [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00012066.2|TREMBL:A8K7X6|ENSEMBL:ENSP00000448762|REFSEQ:NP_114366 Tax_Id=9606 Gene_Symbol=PCBP2 poly(rC)-binding protein 2 isoform b [ipi.HUMAN.20110912.fasta]
  • Isoform 3 of Poly(rC)-binding protein 2 GN=PCBP2 [Doctor+uniprot-HUMAN-120911.fasta]
  • Isoform 3 of Poly(rC)-binding protein 2 OS=Homo sapiens GN=PCBP2 [102012_WuLab_Hsapiens.fasta]
  • Isoform of Q15366, Isoform 3 of Poly(rC)-binding protein 2 OS=Homo sapiens GN=PCBP2 [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 362 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTGVIEGGL NVTLTIRLLM HGKEVGSIIG KKGESVKKMR EESGARINIS EGNCPERIIT  60
   61 LAGPTNAIFK AFAMIIDKLE EDISSSMTNS TAASRPPVTL RLVVPASQCG SLIGKGGCKI 120
  121 KEIRESTGAQ VQVAGDMLPN STERAITIAG IPQSIIECVK QICVVMLESP PKGVTIPYRP 180
  181 KPSSSPVIFA GGQDRYSTGS DSASFPHTTP SMCLNPDLEG PPLEAYTIQG QYAIPQPDLT 240
  241 KLHQLAMQQS HFPMTHGNTG FSGIESSSPE VKGYWAGLDA SAQTTSHELT IPNDLIGCII 300
  301 GRQGAKINEI RQMSGAQIKI ANPVEGSTDR QVTITGSAAS ISLAQYLINV RLSSETGGMG 360
  361 SS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] PSI-BLAST 12.69897 Crystal Structure of KH1 domain of human Poly(C)-binding protein-2 with C-rich strand of human telomeric DNA
    2 View Details [85..181] PSI-BLAST 6.69897 S1 RNA BINDING DOMAIN, NMR, 20 STRUCTURES
    3 View Details [182..281] deduced N/A No confident structure predictions are available.
    4 View Details [282..362] PSI-BLAST 15.69897 Crsytal Structure of domain 3 of human alpha polyC binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  6.76415077523249 bayes_pls_golite062009
  • mRNA binding
    		•  5.07455187994216 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.78650555542715 bayes_pls_golite062009
  • binding
    		•  3.45962790790935 bayes_pls_golite062009
    		• 2.87067043110488 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.28364833275102 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  2.05765562493656 bayes_pls_golite062009
  • DNA binding
    		•  2.03207983673692 bayes_pls_golite062009
  • transcription factor activity
    		•  1.30278154718684 bayes_pls_golite062009
  • protein binding
    		•  1.16541072642796 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.981003625136521 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.722090816226222 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.392035003865213 bayes_pls_golite062009
  • transcription activator activity
    		•  0.324382863054631 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.32222928997178 bayes_pls_golite062009
  • transcription factor binding
    		•  0.254024117548226 bayes_pls_golite062009
  • catalytic activity
    		•  0.113112541746059 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.1069917291606 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0321875054165348 bayes_pls_golite062009
    2
    Term Confidence Notes
  • nucleic acid binding
    		•  4.29626483284963 bayes_pls_golite062009
  • RNA binding
    		•  3.99161318590718 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  3.61794338675663 bayes_pls_golite062009
  • DNA binding
    		•  3.53568546959418 bayes_pls_golite062009
  • structural molecule activity
    		•  3.02980744557801 bayes_pls_golite062009
  • binding
    		•  2.83465364476231 bayes_pls_golite062009
    		• 2.80746531284205 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.84350127337404 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.81524862921454 bayes_pls_golite062009
  • mRNA binding
    		•  1.660993824641 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.62996999055328 bayes_pls_golite062009
  • transcription factor activity
    		•  1.21526211005888 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.19236946227657 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.15212468568198 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.10445667068538 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.85691075793641 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.83268201349295 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.635129001787169 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.477127926059749 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.477127926059749 bayes_pls_golite062009
  • transferase activity
    		•  0.249054945579328 bayes_pls_golite062009
  • translation regulator activity
    		•  0.22908707234671 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.179682348023561 bayes_pls_golite062009
  • protein binding
    		•  0.152645195799531 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.11625379846973 bayes_pls_golite062009
    3
    Term Confidence Notes
  • RNA binding
    		•  6.76415077523249 bayes_pls_golite062009
  • mRNA binding
    		•  5.07455187994216 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.78650555542715 bayes_pls_golite062009
  • binding
    		•  3.45962790790935 bayes_pls_golite062009
    		• 2.87067043110488 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.28364833275102 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  2.05765562493656 bayes_pls_golite062009
  • DNA binding
    		•  2.03207983673692 bayes_pls_golite062009
  • transcription factor activity
    		•  1.30278154718684 bayes_pls_golite062009
  • protein binding
    		•  1.16541072642796 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.981003625136521 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.722090816226222 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.392035003865213 bayes_pls_golite062009
  • transcription activator activity
    		•  0.324382863054631 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.32222928997178 bayes_pls_golite062009
  • transcription factor binding
    		•  0.254024117548226 bayes_pls_golite062009
  • catalytic activity
    		•  0.113112541746059 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.1069917291606 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0321875054165348 bayes_pls_golite062009
    4
    Term Confidence Notes
  • RNA binding
    		•  6.76415077523249 bayes_pls_golite062009
  • mRNA binding
    		•  5.07455187994216 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.78650555542715 bayes_pls_golite062009
  • binding
    		•  3.45962790790935 bayes_pls_golite062009
    		• 2.87067043110488 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.28364833275102 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  2.05765562493656 bayes_pls_golite062009
  • DNA binding
    		•  2.03207983673692 bayes_pls_golite062009
  • transcription factor activity
    		•  1.30278154718684 bayes_pls_golite062009
  • protein binding
    		•  1.16541072642796 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.981003625136521 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.722090816226222 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.392035003865213 bayes_pls_golite062009
  • transcription activator activity
    		•  0.324382863054631 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.32222928997178 bayes_pls_golite062009
  • transcription factor binding
    		•  0.254024117548226 bayes_pls_golite062009
  • catalytic activity
    		•  0.113112541746059 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.1069917291606 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0321875054165348 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle