Protein Overview: YPR158W-B

General Information:
Name(s) found:	YPR158W-B [SGD]
Description(s) found: SHOW ONLY BEST	gi\|7839209\|ref\|NP_058193.1\| Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retrov [NCBI NR] gi\|134039194\|sp\|P0C2J0.1\|YP13B_YEAST RecName: Full=Transposon Ty1-PR2 Gag-Pol polyprotein; AltName: Full=Gag-Pol-p199; AltName: Full=Transposon Ty1 TYA-TYB polyprotein; AltName: Full=TY1A-TY1B; AltName: Full=p190; Contains: RecName: Full=Capsid protein; S [NCBI NR] Transposon Ty1-PR2 Gag-Pol polyprotein OS=Saccharomyces cerevisiae GN=TY1B-PR2 PE=1 SV=1 [Swiss-Prot] Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes [SGD] Chr XVI from 844703-846007,846009-849974 [hmr_yeast5_DM3-1_pombe.fasta] Chr XVI from 844704-846008,846010-849975 [yeastorf3.fasta] YPR158W-B, Chr XVI from 844704-846008,846010-849975 [yeast_orfs2] YPR158W-B SGDID:S0007364, Chr XVI from 844703-846007,846009-849974, Ty ORF [yeastflysequest.fasta] YPR158W-B SGDID:S0007364, Chr XVI from 844705-846009,846011-849976, Ty ORF [10112005cervSGD.fasta] TyB Gag-Pol protein; proteolytically processed to make the Gag, RT, PR, and IN proteins that are required for retrotransposition [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas] YPR158W-B SGDID:S000007364, Chr XVI from 844705-846009,846011-849976, transposable_element_gene, "TyB Gag-Pol protein; proteolytically processed to make the Gag, RT, PR, and IN proteins that are required for retrotransposition" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YPR158W-B SGDID:S000007364, Chr XVI from 844705-846009,846011-849976, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse tr [yeast-contam.fasta] Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes; Ypr158w-bp [Sacc [nr-271106-contam.fasta] YPR158W-B SGDID:S000007364, Chr XVI from 844705-846009,846011-849976, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Transposon Ty1-PR2 Gag-Pol polyprotein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TY1B-PR2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YPR158W-B SGDID:S000007364, Chr XVI from 844709-846013,846015-849980, Genome Release 64-1-1, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" [yeast-030211-contam.fasta] Transposon Ty1-PR2 Gag-Pol polyprotein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TY1B-PR2 PE=3 SV=1 [YEAST.fasta.20131015] YPR158W-B SGDID:S000007364, Chr XVI from 844709-846013,846015-849980, Genome Release 64-2-1, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" [20141208_orf_trans.fasta]
Organism:	Saccharomyces cerevisiae
Length:	1756 amino acids
Gene Ontology:
Cellular Component:	retrotransposon nucleocapsid [ISS]
Biological Process:	transposition, RNA-mediated [ISS]
Molecular Function:	DNA-directed DNA polymerase activity [ISS] RNA-directed DNA polymerase activity [ISS] RNA binding [ISS] protein binding [ISS] ribonuclease activity [ISS] peptidase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESQQLSNYP HISHGSACAS VTSKEVHTNQ DPLDVSASKI QEYDKASTKA NSQQTTTPAS  60
   61 SAVPENPHHA SPQPASVPPP QNGPYPQQCM MTQNQANPSG WSFYGHPSMI PYTPYQMSPM 120
  121 YFPPGPQSQF PQYPSSVGTP LSTPSPESGN TFTDSSSADS DMTSTKKYVR PPPMLTSPND 180
  181 FPNWVKTYIK FLQNSNLGGI IPTVNGKPVR PITDDELTFL YNTFQIFAPS QFLPTWVKDI 240
  241 LSVDYTDIMK ILSKSIEKMQ SDTQEANDIV TLANLQYNGS TPADAFETKV TNIIDRLNNN 300
  301 GIHINNKVAC QLIMRGLSGE YKFLRYTRHR HLNMTVAELF LDIHAIYEEQ QGSRNSKPNY 360
  361 RRNPSDEKND SRSYTNTTKP KVIARNPQKT NNSKSKTARA HNVSTSNNSP STDNDSISKS 420
  421 TTEPIQLNNK HDLHLGQKLT ESTVNHTNHS DDELPGHLLL DSGASRTLIR SAHHIHSASS 480
  481 NPDINVVDAQ KRNIPINAIG DLQFHFQDNT KTSIKVLHTP NIAYDLLSLN ELAAVDITAC 540
  541 FTKNVLERSD GTVLAPIVKY GDFYWVSKKY LLPSNISVPT INNVHTSEST RKYPYPFIHR 600
  601 MLAHANAQTI RYSLKNNTIT YFNESDVDWS SAIDYQCPDC LIGKSTKHRH IKGSRLKYQN 660
  661 SYEPFQYLHT DIFGPVHNLP KSAPSYFISF TDETTKFRWV YPLHDRREDS ILDVFTTILA 720
  721 FIKNQFQASV LVIQMDRGSE YTNRTLHKFL EKKNGITPCY TTTADSRAHG VAERLNRTLL 780
  781 DDCRTQLQCS GLPNHLWFSA IEFSTIVRNS LASPKSKKSA RQHAGLAGLD ISTLLPFGQP 840
  841 VIVNDHNPNS KIHPRGIPGY ALHPSRNSYG YIIYLPSLKK TVDTTNYVIL QGKESRLDQF 900
  901 NYDALTFDED LNRLTASYHS FIASNEIQES NDLNIESDHD FQSDIELHPE QPRNVLSKAV 960
  961 SPTDSTPPST HTEDSKRVSK TNIRAPREVD PNISESNILP SKKRSSTPQI SNIESTGSGG1020
 1021 MHKLNVPLLA PMSQSNTHES SHASKSKDFR HSDSYSENET NHTNVPISST GGTNNKTVPQ1080
 1081 ISDQETEKRI IHRSPSIDAS PPENNSSHNI VPIKTPTTVS EQNTEESIIA DLPLPDLPPE1140
 1141 SPTEFPDPFK ELPPINSHQT NSSLGGIGDS NAYTTINSKK RSLEDNETEI KVSRDTWNTK1200
 1201 NMRSLEPPRS KKRIHLIAAV KAVKSIKPIR TTLRYDEAIT YNKDIKEKEK YIEAYHKEVN1260
 1261 QLLKMNTWDT DKYYDRKEID PKRVINSMFI FNRKRDGTHK ARFVARGDIQ HPDTYDSGMQ1320
 1321 SNTVHHYALM TSLSLALDNN YYITQLDISS AYLYADIKEE LYIRPPPHLG MNDKLIRLKK1380
 1381 SLYGLKQSGA NWYETIKSYL IKQCGMEEVR GWSCVFKNSQ VTICLFVDDM ILFSKDLNAN1440
 1441 KKIITTLKKQ YDTKIINLGE SDNEIQYDIL GLEIKYQRGK YMKLGMENSL TEKIPKLNVP1500
 1501 LNPKGRKLSA PGQPGLYIDQ DELEIDEDEY KEKVHEMQKL IGLASYVGYK FRFDLLYYIN1560
 1561 TLAQHILFPS RQVLDMTYEL IQFMWDTRDK QLIWHKNKPT EPDNKLVAIS DASYGNQPYY1620
 1621 KSQIGNIYLL NGKVIGGKST KASLTCTSTT EAEIHAISES VPLLNNLSHL VQELNKKPIT1680
 1681 KGLLTDSKST ISIIISNNEE KFRNRFFGTK AMRLRDEVSG NHLHVCYIET KKNIADVMTK1740
 1741 PLPIKTFKLL TNKWIH

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		YDR034C-D YDR210C-C YDR210C-D YDR210W-B YDR261W-B YFL002W-A, YGR161W-B YGR027W-B YGR109W-B YLR157C-B YNL284C-B YOR142W-B YOR192C-B YOR343W-A YOR343W-B YPR137C-B YPR158C-D YPR158W-B

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	his-HA tag on RPA135	Schneider, DA, et al. (2006)
View Run	MLP2	#26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: YPR158W-B

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: