Protein Overview: VPS66

General Information:
Name(s) found:	VPS66 / YPR139C [SGD]
Description(s) found: Found 32 descriptions. SHOW ALL	Cytoplasmic protein of unknown function involved in vacuolar protein sorting. [SGD]
Organism:	Saccharomyces cerevisiae
Length:	300 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	protein targeting to vacuole [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKYTNWRDN GTGIAPFLPN TIRKPSKVMT ACLLGILGVK TIIMLPLIML YLLTGQNNLL  60
   61 GLILKFTFSW KEEITVQGIK KRDVRKSKHY PQKGKLYICN CTSPLDAFSV VLLAQGPVTL 120
  121 LVPSNDIVYK VSIREFINFI LAGGLDIKLY GHEVAELSQL GNTVNFMFAE GTSCNGKSVL 180
  181 PFSITGKKLK EFIDPSITTM NPAMAKTKKF ELQTIQIKTN KTAITTLPIS NMEYLSRFLN 240
  241 KGINVKCKIN EPQVLSDNLE ELRVALNGGD KYKLVSRKLD VESKRNFVKE YISDQRKKRK 300
  301

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#25 Asynchronous Prep3-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	UMP1	VPS66	1	Unpublished Fields Lab Data
View Screen	RPN9	VPS66	1	Unpublished Fields Lab Data
View Screen	UBC7	VPS66	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	VPS66	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..205]	MSA	128.341997	View MSA. No confident structure predictions are available.
2	View Details	[206..300]	deduced	N/A	Confident ab initio structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2