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Protein Overview: DBF20

General Information:
Name(s) found: DBF20 / YPR111W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 564 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: protein amino acid phosphorylation [IDALink to PubMed article]
    cell cycle [IEPLink to PubMed article][IGILink to PubMed article]
    Molecular Function: protein serine/threonine kinase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSRSDREVD DLAGNMSHLG FYDLNIPKPT SPQAQYRPAR KSENGRLTPG LPRSYKPCDS  60
   61 DDQDTFKNRI SLNHSPKKLP KDFHERASQS KTQRVVNVCQ LYFLDYYCDM FDYVISRRQR 120
  121 TKQVLRYLEQ QRSVKNVSNK VLNEEWALYL QREHEVLRKR RLKPKHKDFQ ILTQVGQGGY 180
  181 GQVYLAKKKD SDEICALKIL NKKLLFKLNE TNHVLTERDI LTTTRSDWLV KLLYAFQDPE 240
  241 SLYLAMEFVP GGDFRTLLIN TRILKSGHAR FYISEMFCAV NALHELGYTH RDLKPENFLI 300
  301 DATGHIKLTD FGLAAGTVSN ERIESMKIRL EEVKNLEFPA FTERSIEDRR KIYHNMRKTE 360
  361 INYANSMVGS PDYMALEVLE GKKYDFTVDY WSLGCMLFES LVGYTPFSGS STNETYENLR 420
  421 YWKKTLRRPR TEDRRAAFSD RTWDLITRLI ADPINRVRSF EQVRKMSYFA EINFETLRTS 480
  481 SPPFIPQLDD ETDAGYFDDF TNEEDMAKYA DVFKRQNKLS AMVDDSAVDS KLVGFTFRHR 540
  541 DGKQGSSGIL YNGSEHSDPF STFY

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ALA1 AXL1 DBF20 EGD2 GPH1 IDH2 MOB1 RPB10

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC48 DBF20 1 Unpublished Fields Lab Data
    View Screen REH1 DBF20 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data DBF20 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] deduced N/A No confident structure predictions are available.
    2 View Details [167..564] PSI-BLAST 57.0 Crystal Structure of ROCK 1 bound to fasudil


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle