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Protein Overview: COX11

General Information:
Name(s) found: COX11 / YPL132W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Mitochondrial inner membrane protein required for delivery of copper to the Cox1p subunit of cytochrome c oxidase; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 300 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial ribosome [IDALink to PubMed article]
    mitochondrial envelope [IDALink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed articleLink to PubMed article]
    Biological Process: protein complex assembly [IMPLink to PubMed article]
    aerobic respiration [IMPLink to PubMed article]
    Molecular Function: copper ion binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRICPIVRS KVPLLGTFLR SDSWLAPHAL ALRRAICKNV ALRSYSVNSE QPKHTFDISK  60
   61 LTRNEIQQLR ELKRARERKF KDRTVAFYFS SVAVLFLGLA YAAVPLYRAI CARTGFGGIP 120
  121 ITDRRKFTDD KLIPVDTEKR IRISFTSEVS QILPWKFVPQ QREVYVLPGE TALAFYKAKN 180
  181 YSDKDIIGMA TYSIAPGEAA QYFNKIQCFC FEEQKLAAGE EIDMPVFFFI DPDFASDPAM 240
  241 RNIDDIILHY TFFRAHYGDG TAVSDSKKEP EMNADEKAAS LANAAILSPE VIDTRKDNSN 300
  301

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) COB COX1 COX11 COX2 COX3 MRPS17 SCO1 VAR1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..300] MSA 35.054957 View MSA. No confident structure predictions are available.
    2 View Details [83..300] PSI-BLAST 63.30103 Solution Structure of apoCox11, 30 structures

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • structural molecule activity
    		•  4.47117060684776 bayes_pls_golite062009
  • cytochrome-c oxidase activity
    		•  1.63692440621606 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors
    		•  1.63692440621606 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors, oxygen as acceptor
    		•  1.63692440621606 bayes_pls_golite062009
  • heme-copper terminal oxidase activity
    		•  1.45348828463274 bayes_pls_golite062009
  • binding
    		•  1.26238051646126 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.03472539732492 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  0.401392171756694 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.312235007946628 bayes_pls_golite062009
  • copper ion binding
    		•  0.19463795974816 bayes_pls_golite062009
  • catalytic activity
    		•  0.176396048613815 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.0231690475060109 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0170756391184381 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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