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View Structure Prediction Details

Protein: COX11
Organism: Saccharomyces cerevisiae
Length: 300 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX11.

Description E-value Query
Range
Subject
Range
gi|190407826 - gi|190407826|gb|EDV11091.1| cytochrome c oxidase assembly protein COX11, mitochondrial precursor [Sa...
gi|207340612 - gi|207340612|gb|EDZ68909.1| YPL132Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151942666 - gi|151942666|gb|EDN61012.1| cytochrome C oxidase [Saccharomyces cerevisiae YJM789]
COX11 - Mitochondrial inner membrane protein required for delivery of copper to the Cox1p subunit of cytochr...
COX11_YEAST - Cytochrome c oxidase assembly protein COX11, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC ...
0.0 [1..300] [1..300]
CG31648-PA - This gene is referred to in FlyBase by the symbol Dmel\CG31648 (CG31648, FBgn0051648). It is a prote...
gi|220959534, gi... - gi|220959534|gb|ACL92310.1| CG31648-PA [synthetic construct], gi|220950848|gb|ACL87967.1| CG31648-PA...
2.0E-81 [42..258] [2..225]
COX11 - COX11 cytochrome c oxidase assembly homolog (yeast)
gi|60814946 - gi|60814946|gb|AAX36326.1| COX11-like cytochrome c oxidase assembly protein [synthetic construct]
2.0E-77 [60..263] [72..272]
gi|13810231 - gi|13810231|emb|CAC37420.1| SPAC19B12.13 [Schizosaccharomyces pombe]
6.0E-75 [40..258] [490..722]
COXZ_RECAM - Cytochrome c oxidase assembly protein ctaG OS=Reclinomonas americana GN=CTAG PE=3 SV=1
4.0E-68 [80..257] [2..181]
gi|25310033 - gi|25310033|pir||AI3434 cytochrome c oxidase assembly protein ctaG [imported] - Brucella melitensis ...
gi|17983467, gi|... - gi|17987746|ref|NP_540380.1| cytochrome C oxidase assembly protein [Brucella melitensis 16M], gi|179...
6.0E-68 [76..268] [45..229]
gi|125545526 - gi|125545526|gb|EAY91665.1| hypothetical protein OsI_13305 [Oryza sativa Indica Group]
gi|108710775, gi... - gi|50918355|ref|XP_469574.1| putative cytochrome c oxidase assembly protein [Oryza sativa (japonica ...
7.0E-68 [75..258] [58..244]

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Predicted Domain #1
Region A:
Residues: [1-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRICPIVRS KVPLLGTFLR SDSWLAPHAL ALRRAICKNV ALRSYSVNSE QPKHTFDISK  60
   61 LTRNEIQQLR ELKRARERKF KDRTVAFYFS SVAVLFLGLA YAAVPLYRAI CARTGFGGIP 120
  121 ITDRRKFTDD KLIPVDTEKR IRISFTSEVS QILPWKFVPQ QREVYVLPGE TALAFYKAKN 180
  181 YSDKDIIGMA TYSIAPGEAA QYFNKIQCFC FEEQKLAAGE EIDMPVFFFI DPDFASDPAM 240
  241 RNIDDIILHY TFFRAHYGDG TAVSDSKKEP EMNADEKAAS LANAAILSPE VIDTRKDNSN 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [83-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTVAFYFSSV AVLFLGLAYA AVPLYRAICA RTGFGGIPIT DRRKFTDDKL IPVDTEKRIR  60
   61 ISFTSEVSQI LPWKFVPQQR EVYVLPGETA LAFYKAKNYS DKDIIGMATY SIAPGEAAQY 120
  121 FNKIQCFCFE EQKLAAGEEI DMPVFFFIDP DFASDPAMRN IDDIILHYTF FRAHYGDGTA 180
  181 VSDSKKEPEM NADEKAASLA NAAILSPEVI DTRKDNSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.30103
Match: 1so9A
Description: Solution Structure of apoCox11, 30 structures
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural molecule activity 4.47117060684776 bayes_pls_golite062009
cytochrome-c oxidase activity 1.63692440621606 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 1.63692440621606 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 1.63692440621606 bayes_pls_golite062009
heme-copper terminal oxidase activity 1.45348828463274 bayes_pls_golite062009
binding 1.26238051646126 bayes_pls_golite062009
oxidoreductase activity 1.03472539732492 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.401392171756694 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.312235007946628 bayes_pls_golite062009
copper ion binding 0.19463795974816 bayes_pls_golite062009
catalytic activity 0.176396048613815 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.0231690475060109 bayes_pls_golite062009
cation transmembrane transporter activity 0.0170756391184381 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle