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Protein Overview: MSC6

General Information:
Name(s) found: MSC6 / YOR354C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 692 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: reciprocal meiotic recombination [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSHNALRAF DCSKVIISRR CLTSSTSIYQ QSSVHLQETD DGHSGNREKH VSPFERVQNL  60
   61 AADLKNELKA PDSDINEVFN DFKDKIESLK QKLRNPSPME RSHLLANFSS DLLQELSYRS 120
  121 KNMTLDPYQV LNTLCQYKLA RSQHFTIVLK YLLYNQSPQD VIALWVKYLE TISENPVILL 180
  181 QNSSSRAHMQ NIAITTIAYL SLPENTVDIN ILYKILQIDR KMGQVLPFNM IRRMLSTEFS 240
  241 SLERRDVIIK NLNTLYYQYT VQDSDHFLSQ IENAPRWIDL RDLYGQYNKL EGEKNVEIIS 300
  301 KFMDKFIDLD KPDQVVTIYN QYSKVFPNST SLKDCLLRAV SHLRAKSSKE KLDRILAVWN 360
  361 SVIKPGDNIK NTSYATLVNA LTDSGNFNHL KEFWEEELPK KFKKDPIVKE AFLLALCQTS 420
  421 PLKYDQVKGE LAETVKTKKL FNKVLLLMLD DEKVSEEQFN TFYYNHYPSD GVLPPTLDTL 480
  481 SIKMYANYKF QAEDTRPQFD LLQSVSINPT DYEKVEKITK AFISVCPTVE PIRQLYKQLG 540
  541 THLNARNYAD FISAEFNKPD GTVAEAKNLF SDFLSYQKTR KRNVDNTPLN ALLLGFCDKL 600
  601 YKSKHSEYVP YIEKYYNLAK DSSIRVSNLA VSKILFNLAT FARNTQQLSD KEVAFINQFM 660
  661 RDLGTNEGFR PNPKDIQILK ECDGITVPEK LT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run BIR1 No Comments Widlund PO, et al. (2005)
    View Run ASF1 3906: TAP-tagged Green EM, et al (2005)
    View Run ASF1 3912: TAP-tagged, strain background includes hpc2(delta) Green EM, et al (2005)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MSC6 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..692] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle