Protein Overview: FRT1

General Information:
Name(s) found:	FRT1 / YOR324C [SGD]
Description(s) found: Found 31 descriptions. SHOW ALL	Tail-anchored, endoplasmic reticulum membrane protein that is a substrate of the phosphatase calcineurin, interacts with homolog Frt2p, promotes cell growth in conditions of high Na+, alkaline pH, and cell wall stress [SGD]
Organism:	Saccharomyces cerevisiae
Length:	602 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA ]
Biological Process:	response to stress [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLLIDRMEN PGSRNCTLLP PSFPRGFCKG RRASSGDAVK IKESGLQPQP QPEPLQAKTN  60
   61 VAHFSKSSSR LPVIAVNDNP VVPRPSTEVN LGSLLQKERE KEKEEQPALH DRRHLYVTKN 120
  121 RAHGVRQRSL EMTSLPVLGS TKTGKFSDFL FEDDIDNRVG RHSRSYSGAS SLDDPFRVSP 180
  181 KTDFNSNRAR LSCLSKGRRG SMSVFQSCHT GLAFNQIQGS SSSQRRSSAG SFDYERKRLV 240
  241 NQFLQPSLGN SDPFDTLRES VVFEPSSTAG GIKLGNMHSQ SQISVNSSPS TSLFYHDLDG 300
  301 SAVNDSSSFL YSRSNVPAFL SSSAFSSTSS TSSDSEDVDR RSLNGVYPSL GYLTNQRKPR 360
  361 NSSGSSTAPG TDTLGFKYLL NRQKSADSST RFKSVLKVNN NNGSAATPDS SSNSISKSNS 420
  421 NLNDNIDELN YYQNHISTLL VKIENEMRRN LNDTIIKNEN NVQKTIQKYD LLSGELTLLL 480
  481 DEMTTLRTTV INQFLVKLKS DFDEDDNKAF INELKISVEE SVAQLQGLER RMEVCQERLN 540
  541 KQKSSLREMD SLIELKNVLN KSKNNTKSIY LYRYFIIDII AFLLMGGFIV YVKNLLTRFF 600
  601 TR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#03 Alpha Factor Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#29 Asynchronous Prep5-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	IMP4	FRT1	2	Unpublished Fields Lab Data
View Screen	SPO21	FRT1	2	Unpublished Fields Lab Data
View Screen	NOG1	FRT1	2	Unpublished Fields Lab Data
View Screen	FRT2	FRT1	2	Unpublished Fields Lab Data
View Screen	TCP1	FRT1	2	Unpublished Fields Lab Data
View Screen	FMP48	FRT1	2	Unpublished Fields Lab Data
View Screen	SST2	FRT1	2	Unpublished Fields Lab Data
View Screen	ELA1	FRT1	1	Unpublished Fields Lab Data
View Screen	SMC5	FRT1	1	Hazbun TR, et al. (2003)
View Screen	TEL1	FRT1	1	Unpublished Fields Lab Data
View Screen	EST1	FRT1	1	Unpublished Fields Lab Data
View Screen	MEC3	FRT1	1	Unpublished Fields Lab Data
View Screen	CNA1	FRT1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	FRT1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..154]	deduced	N/A	No confident structure predictions are available.
2	View Details	[155..602]	PSI-BLAST	25.30103	Heavy meromyosin subfragment

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2