Protein Overview: MCH5

General Information:
Name(s) found:	MCH5 / YOR306C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74645014\|sp\|Q08777.1\|MCH5_YEAST RecName: Full=Riboflavin transporter MCH5 [NCBI NR] gi\|6324882\|ref\|NP_014951.1\| Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylat [NCBI NR] pir\|\|S67210 probable membrane protein YOR306c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1420675\|emb\|CAA99626.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Riboflavin transporter MCH5 OS=Saccharomyces cerevisiae GN=MCH5 PE=1 SV=1 [Swiss-Prot] MCH5 Transporter not monocarboxylate permease [mips] Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport [SGD] >Q08777 (Q08777) Chromosome XV reading frame ORF YOR306C [4932.FASTACCERV.txt] Chr XV from 891426-889861, reverse complement [hmr_yeast5_DM3-1_pombe.fasta] Chr XV from 889860-891425, reverse complement [yeastorf3.fasta] Chr XV from 889861-891426, reverse complement [yeastorf4.fasta] YOR306C, Chr XV from 889860-891425, reverse complement [yeast_orfs2] MCH5 SGDID:S0005833, Chr XV from 891428-889863, reverse complement, Verified ORF [yeastflysequest.fasta] Mch5p [Saccharomyces cerevisiae]gi\|1420675\|emb\|CAA99626.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|2132942\|pir\|\|S67210 probable membrane protein YOR306c - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas] (Q08777) S.cerevisiae chromosome XV reading frame ORF YOR306c [cerv4932.FASTAC] MCH5 SGDID:S000005833, Chr XV from 891428-889863, reverse complement, Verified ORF, "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficien [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] MCH5 SGDID:S000005833, Chr XV from 891430-889865, reverse complement, Verified ORF, "Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate perme [yeast-contam.fasta] Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport; Mch5p [Saccharo [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] MCH5 SGDID:S000005833, Chr XV from 891430-889865, reverse complement, Verified ORF, "Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport" [yeast-bovrabprots.fasta] [chemostatdb.fasta]
Organism:	Saccharomyces cerevisiae
Length:	521 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [IDA]
Biological Process:	riboflavin transport [IGI]
Molecular Function:	riboflavin transporter activity [IGI] [NOT]monocarboxylic acid transmembrane transporter activity [IGI][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDSLTPKD TIVPEEQTNQ LRQPDLDEDS IHYDPEADDL ESLETTASYA STSVSAKVYT  60
   61 KKEVNKGTDI ESQPHWGENT SSTHDSDKEE DSNEEIESFP EGGFKAWVVT FGCFLGLIAC 120
  121 FGLLNSTGVI ESHLQDNQLS SESVSTIGWL FSLFLFVCSA SCIISGTYFD RNGFRTIMIV 180
  181 GTVFHVAGLF ATANSTKYWH FILSFAIVCG FGNGIVLSPL VSVPAHYFFK RRGTALAMAT 240
  241 IGGSVGGVVF PIMLRSFFSM KSDTDPTYGF VWGIRTLGFL DLALLTLSII LVKERLPHVI 300
  301 ENSKDGESRW RYILRVYILQ CFDAKAFLDM KYLFCVLGTV FSELSINSAL TYYGSYATSH 360
  361 GISANDAYTL IMIINVCGIP GRWVPGYLSD KFGRFNVAIA TLLTLFIVMF VGWLPFGTNL 420
  421 TNMYVISALY GFCSGSVFSL LPVCCGQISK TEEFGKRYST MYFVVGFGTL VGIPITGAII 480
  481 SIKTTADYQH YIIFSGLATF VSAVCYIISR AYCVGFKWVR F

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		AGP2 BIO5 MCH5 THI7 TPN1 VHT1

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..82]	deduced	N/A	No confident structure predictions are available.
2	View Details	[83..521]	Pfam	3.070581	Sugar (and other) transporter No confident structure predictions are available.

Protein Overview: MCH5

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: