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Protein Overview: PNT1

General Information:
Name(s) found: PNT1 / YOR266W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Mitochondrial integral inner membrane protein involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p; deletion mutant sensitive to the anti-Pneumocystis carinii drug pentamidine [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 423 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: inner mitochondrial membrane organization [IMPLink to PubMed article]
    Molecular Function: molecular_function [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSRVALVRK YIAPSVIKSD SIQLHGLVKA PLFKALNSRY KLGSLQIVQD VDWNAKTTPS  60
   61 DSPEPLAATL NSNRSLPMTK FPKQEILEQV KLDTKVGKWR KFMTGWFRIG LYLLKSYKTG 120
  121 IQNTLKVFWD TRNEEQKFSI KNGALANLVR EIEMHEINTR LSSSSLPTSS SAKAPLRPLS 180
  181 INRKTLVELI RRDQIWKLPV FFTLVFIFEE VSVLIFTFFP RVCPYNCLTP GGYKKLSNSY 240
  241 IKGTTSTQGN YGLGPLEFTK QGTIKYEPPY AVPIENLYNF LTSFPQSMIS NWKLYIYKKL 300
  301 KLQKLLCNEI EKIYQYLFID DWLLLQSILN TDVEKTKIAL SDRELVNCIL ERKLYHMGDD 360
  361 LNEMVNDTLG KEILLKRLFL YWTLRYNDTI SLNGKHTFSE KWGVNNISLL KYNSELVATK 420
  421 DIQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) MCK1 PNT1 SLM1 TRM3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PNT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..423] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.61

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle