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Protein Overview: HAL9

General Information:
Name(s) found: HAL9 / YOL089C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1030 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: response to salt stress [IMPLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [IMPLink to PubMed article]
    Molecular Function: specific RNA polymerase II transcription factor activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENQGGDYSP NGFSNSASNM NAVFNNEITG RSDISNVNHQ TGTPRLVPET QIWSMPVPDQ  60
   61 LMTMPNRENT LMTGSTIGPN IPMNVAYPNT IYSPTEHQSQ FQTQQNRDIS TMMEHTNSND 120
  121 MSGSGKNLKK RVSKACDHCR KRKIRCDEVD QQTKKCSNCI KFQLPCTFKH RDEILKKKRK 180
  181 LEIKHHATPG ESLQTSNSIS NPVASSSVPN SGRFELLNGN SPLESNIIDK VSNIQNNLNK 240
  241 KMNSKIEKLD RKMSYIIDSV ARLEWLLDKA VKKQEGKYKE KNNLPKPARK IYSTALLTAQ 300
  301 KLYWFKQSLG VKASNEEFLS PISEILSISL KWYATQMKKF MDLSSPAFFS SEIILYSLPP 360
  361 KKQAKRLLEN FHATLLSSVT GIISLKECLD LAEKYYSESG EKLTYPEHLL LNVCLCSGAS 420
  421 ATQSIIRGDS KFLRKDRYDP TSQELKKIEN VALLNAMYYY HKLSTICSGT RTLQALLLLN 480
  481 RYFQLTYDTE LANCILGTAI RLAVDMELNR KSSYKSLDFE EAIRRRRMWW HCFCTDKLYS 540
  541 LMLSRPPIVG ERDMDMLTDQ NYYEVIKTNI LPDLIDKKED LDKITDVNSA LNVVVNFCQH 600
  601 ISLFISYYVS KLVSIESKIY STCFAVRSTL DLSFDAMLDK IKDLNDSLNN WRDNLHVSMK 660
  661 LKSYKQYLSV LYAQKSQENP ALSFEIACSR VLNCHFRALY SKVILSMMTT SLLIDNERLY 720
  721 KGSRHDIPQL FILFSSQYLN ASKEMLQLFQ GINYQAHMYN EVMYQFSTAM FVLFFYVVDN 780
  781 MNDLKKKGEV KEIIDILKKS YDRLVGENDE QLLFDNVKWN TLIVFYSHFL KYVLQRYHAL 840
  841 NDSTSIFDSK PYDETITKVI MHSRKIKDET VDQLIMSLKS YGSLHSLQKG NEADLADDGL 900
  901 NTNDISSEDF AEEAPINLFG ELSVEILKLL KSHSPISNFG DLSPSSNRKG ISDDSSLYPI 960
  961 RSDLTSLVYP IHSSDTGDTL SSGLETPENS NFNSDSGIKE DFEAFRALLP LGKLIYDRDY1020
 1021 SFVNTFRDYE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run PAN1 No Comments Toshima J, et al (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data HAL9 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..111] MSA 5.178996 View MSA. No confident structure predictions are available.
    2 View Details [112..193] PSI-BLAST 29.37734 Ethanol regulon transcriptional activator ALCR DNA-binding domain
    3 View Details [194..284] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [285..581] MSA 6.179981 View MSA. No confident structure predictions are available.
    5 View Details [582..806] MSA 1.083987 View MSA. No confident structure predictions are available.
    6 View Details [807..1030] deduced N/A No confident structure predictions are available.
    7 View Details [849..1030] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  4.56444258780502 bayes_pls_golite062009
  • DNA binding
    		•  4.01653715768897 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.75642497789214 bayes_pls_golite062009
  • binding
    		•  3.44246337929443 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.93914501897006 bayes_pls_golite062009
  • transcription factor activity
    		•  2.84476696728644 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  2.44382866473054 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.79090232026007 bayes_pls_golite062009
  • transcription activator activity
    		•  0.915626626047549 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle