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View Structure Prediction Details

Protein: HAL9
Organism: Saccharomyces cerevisiae
Length: 1030 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HAL9.

Description E-value Query
Range
Subject
Range
HAL9_YEAST - Halotolerance protein 9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HAL9 PE=1 SV=1
HAL9 - Putative transcription factor containing a zinc finger; overexpression increases salt tolerance thro...
0.0 [1..1030] [1..1030]
gi|168849 - gi|168849|gb|AAA33602.1| pathway-specific regulatory protein [Neurospora crassa]
2.0E-86 [90..801] [7..635]
gi|6901427 - gi|6901427|emb|CAB71797.1| pathway-specific nitrogen regulator [Tolypocladium inflatum]
4.0E-86 [62..804] [1..653]
gi|1706177 - sp|P52959|CT1B_FUSSO CUTINASE TRANSCRIPTION FACTOR 1 BETA
CTF1B_FUSSO - Cutinase transcription factor 1 beta OS=Fusarium solani subsp. pisi GN=CTF1-BETA PE=2 SV=1
7.0E-82 [83..780] [1..645]
NIRA_EMENI - Nitrogen assimilation transcription factor nirA OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 ...
NIRA_EMENI - Nitrogen assimilation transcription factor nirA OS=Emericella nidulans GN=nirA PE=4 SV=1
1.0E-76 [101..804] [7..616]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENQGGDYSP NGFSNSASNM NAVFNNEITG RSDISNVNHQ TGTPRLVPET QIWSMPVPDQ  60
   61 LMTMPNRENT LMTGSTIGPN IPMNVAYPNT IYSPTEHQSQ FQTQQNRDIS T

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [112-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMEHTNSNDM SGSGKNLKKR VSKACDHCRK RKIRCDEVDQ QTKKCSNCIK FQLPCTFKHR  60
   61 DEILKKKRKL EIKHHATPGE SL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.37734
Match: 2alcA_
Description: Ethanol regulon transcriptional activator ALCR DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.01653715768897 bayes_pls_golite062009
nucleic acid binding 3.75642497789214 bayes_pls_golite062009
binding 3.44246337929443 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.93914501897006 bayes_pls_golite062009
transcription factor activity 2.84476696728644 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 2.44382866473054 bayes_pls_golite062009
sequence-specific DNA binding 1.79090232026007 bayes_pls_golite062009
transcription activator activity 0.915626626047549 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [194-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTSNSISNPV ASSSVPNSGR FELLNGNSPL ESNIIDKVSN IQNNLNKKMN SKIEKLDRKM  60
   61 SYIIDSVARL EWLLDKAVKK QEGKYKEKNN L

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.830 0.057 response to salt stress a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain

Predicted Domain #4
Region A:
Residues: [285-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKPARKIYST ALLTAQKLYW FKQSLGVKAS NEEFLSPISE ILSISLKWYA TQMKKFMDLS  60
   61 SPAFFSSEII LYSLPPKKQA KRLLENFHAT LLSSVTGIIS LKECLDLAEK YYSESGEKLT 120
  121 YPEHLLLNVC LCSGASATQS IIRGDSKFLR KDRYDPTSQE LKKIENVALL NAMYYYHKLS 180
  181 TICSGTRTLQ ALLLLNRYFQ LTYDTELANC ILGTAIRLAV DMELNRKSSY KSLDFEEAIR 240
  241 RRRMWWHCFC TDKLYSLMLS RPPIVGERDM DMLTDQNYYE VIKTNILPDL IDKKEDL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [582-806]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKITDVNSAL NVVVNFCQHI SLFISYYVSK LVSIESKIYS TCFAVRSTLD LSFDAMLDKI  60
   61 KDLNDSLNNW RDNLHVSMKL KSYKQYLSVL YAQKSQENPA LSFEIACSRV LNCHFRALYS 120
  121 KVILSMMTTS LLIDNERLYK GSRHDIPQLF ILFSSQYLNA SKEMLQLFQG INYQAHMYNE 180
  181 VMYQFSTAMF VLFFYVVDNM NDLKKKGEVK EIIDILKKSY DRLVG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [807-1030]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENDEQLLFDN VKWNTLIVFY SHFLKYVLQR YHALNDSTSI FDSKPYDETI TKVIMHSRKI  60
   61 KDETVDQLIM SLKSYGSLHS LQKGNEADLA DDGLNTNDIS SEDFAEEAPI NLFGELSVEI 120
  121 LKLLKSHSPI SNFGDLSPSS NRKGISDDSS LYPIRSDLTS LVYPIHSSDT GDTLSSGLET 180
  181 PENSNFNSDS GIKEDFEAFR ALLPLGKLIY DRDYSFVNTF RDYE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [849-1030]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKPYDETITK VIMHSRKIKD ETVDQLIMSL KSYGSLHSLQ KGNEADLADD GLNTNDISSE  60
   61 DFAEEAPINL FGELSVEILK LLKSHSPISN FGDLSPSSNR KGISDDSSLY PIRSDLTSLV 120
  121 YPIHSSDTGD TLSSGLETPE NSNFNSDSGI KEDFEAFRAL LPLGKLIYDR DYSFVNTFRD 180
  181 YE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
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