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View Structure Prediction Details

Protein: HAL9
Organism: Saccharomyces cerevisiae
Length: 1030 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HAL9.

Description E-value Query
Range
Subject
Range
HAL9_YEAST - Halotolerance protein 9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HAL9 PE=1 SV=1
HAL9 - Putative transcription factor containing a zinc finger; overexpression increases salt tolerance thro...
0.0 [1..1030] [1..1030]
gi|168849 - gi|168849|gb|AAA33602.1| pathway-specific regulatory protein [Neurospora crassa]
2.0E-86 [90..801] [7..635]
gi|6901427 - gi|6901427|emb|CAB71797.1| pathway-specific nitrogen regulator [Tolypocladium inflatum]
4.0E-86 [62..804] [1..653]
gi|1706177 - sp|P52959|CT1B_FUSSO CUTINASE TRANSCRIPTION FACTOR 1 BETA
CTF1B_FUSSO - Cutinase transcription factor 1 beta OS=Fusarium solani subsp. pisi GN=CTF1-BETA PE=2 SV=1
7.0E-82 [83..780] [1..645]
NIRA_EMENI - Nitrogen assimilation transcription factor nirA OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 ...
NIRA_EMENI - Nitrogen assimilation transcription factor nirA OS=Emericella nidulans GN=nirA PE=4 SV=1
1.0E-76 [101..804] [7..616]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENQGGDYSP NGFSNSASNM NAVFNNEITG RSDISNVNHQ TGTPRLVPET QIWSMPVPDQ  60
   61 LMTMPNRENT LMTGSTIGPN IPMNVAYPNT IYSPTEHQSQ FQTQQNRDIS T

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.391 0.362 transcription initiation from RNA polymerase II promoter a.74.1 Cyclin-like
View Download 0.307 0.271 response to salt stress a.3.1 Cytochrome c
View Download 0.209 0.033 response to salt stress a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.350 0.018 response to salt stress a.24.4 Hemerythrin
View Download 0.391 N/A N/A a.74.1 Cyclin-like
View Download 0.350 N/A N/A a.24.4 Hemerythrin
View Download 0.209 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin

Predicted Domain #2
Region A:
Residues: [112-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMEHTNSNDM SGSGKNLKKR VSKACDHCRK RKIRCDEVDQ QTKKCSNCIK FQLPCTFKHR  60
   61 DEILKKKRKL EIKHHATPGE SL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.37734
Match: 2alcA_
Description: Ethanol regulon transcriptional activator ALCR DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.01653715768897 bayes_pls_golite062009
nucleic acid binding 3.75642497789214 bayes_pls_golite062009
binding 3.44246337929443 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.93914501897006 bayes_pls_golite062009
transcription factor activity 2.84476696728644 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 2.44382866473054 bayes_pls_golite062009
sequence-specific DNA binding 1.79090232026007 bayes_pls_golite062009
transcription activator activity 0.915626626047549 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [194-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTSNSISNPV ASSSVPNSGR FELLNGNSPL ESNIIDKVSN IQNNLNKKMN SKIEKLDRKM  60
   61 SYIIDSVARL EWLLDKAVKK QEGKYKEKNN L

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.830 0.057 response to salt stress a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.787 0.057 response to salt stress a.47.2 t-snare proteins
View Download 0.720 0.057 response to salt stress a.60.8 HRDC-like
View Download 0.757 0.057 response to salt stress a.118.11 Cytochrome c oxidase subunit E
View Download 0.734 0.057 response to salt stress a.7.6 Ribosomal protein S20
View Download 0.636 0.057 response to salt stress a.51.1 Cytochrome c oxidase subunit h
View Download 0.588 0.057 response to salt stress a.2.2 Ribosomal protein L29 (L29p)
View Download 0.587 0.057 response to salt stress i.1.1 Ribosome and ribosomal fragments
View Download 0.571 0.057 response to salt stress a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.537 0.057 response to salt stress a.60.2 RuvA domain 2-like
View Download 0.506 0.057 response to salt stress a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.463 0.057 response to salt stress a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.441 0.057 response to salt stress a.2.3 Chaperone J-domain
View Download 0.439 0.057 response to salt stress a.4.5 "Winged helix" DNA-binding domain
View Download 0.435 0.057 response to salt stress a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.422 0.057 response to salt stress a.2.3 Chaperone J-domain
View Download 0.422 0.057 response to salt stress a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.412 0.057 response to salt stress a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.405 0.057 response to salt stress a.7.1 Spectrin repeat
View Download 0.399 0.057 response to salt stress a.2.7 tRNA-binding arm
View Download 0.381 0.057 response to salt stress a.4.3 ARID-like
View Download 0.365 0.057 response to salt stress a.118.1 ARM repeat
View Download 0.361 0.057 response to salt stress a.35.1 lambda repressor-like DNA-binding domains
View Download 0.355 0.057 response to salt stress a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.350 0.057 response to salt stress a.118.8 TPR-like
View Download 0.347 0.057 response to salt stress a.36.1 Signal peptide-binding domain
View Download 0.339 0.057 response to salt stress d.6.1 Prion-like
View Download 0.327 0.057 response to salt stress a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.325 0.057 response to salt stress a.4.8 Ribosomal protein S18
View Download 0.324 0.057 response to salt stress a.61.1 Retroviral matrix proteins
View Download 0.319 0.057 response to salt stress f.17.1 F1F0 ATP synthase subunit C
View Download 0.312 0.057 response to salt stress a.50.1 Anaphylotoxins (complement system)
View Download 0.309 0.057 response to salt stress a.60.9 lambda integrase-like, N-terminal domain
View Download 0.303 0.057 response to salt stress a.24.17 Group V grass pollen allergen
View Download 0.299 0.057 response to salt stress d.109.2 C-terminal, gelsolin-like domain of Sec23/24
View Download 0.298 0.057 response to salt stress a.118.12 Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain
View Download 0.298 0.057 response to salt stress a.4.1 Homeodomain-like
View Download 0.296 0.057 response to salt stress a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.290 0.057 response to salt stress a.2.7 tRNA-binding arm
View Download 0.287 0.057 response to salt stress c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.286 0.057 response to salt stress a.23.5 Hemolysin expression modulating protein HHA
View Download 0.284 0.057 response to salt stress a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.278 0.057 response to salt stress a.2.3 Chaperone J-domain
View Download 0.277 0.057 response to salt stress f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.276 0.057 response to salt stress a.2.7 tRNA-binding arm
View Download 0.276 0.057 response to salt stress a.118.9 ENTH/VHS domain
View Download 0.275 0.057 response to salt stress a.118.8 TPR-like
View Download 0.274 0.057 response to salt stress a.16.1 S15/NS1 RNA-binding domain
View Download 0.269 0.057 response to salt stress a.47.2 t-snare proteins
View Download 0.262 0.057 response to salt stress a.3.1 Cytochrome c
View Download 0.261 0.057 response to salt stress a.4.5 "Winged helix" DNA-binding domain
View Download 0.260 0.057 response to salt stress a.16.1 S15/NS1 RNA-binding domain
View Download 0.258 0.057 response to salt stress a.118.14 FliG
View Download 0.254 0.057 response to salt stress a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.252 0.057 response to salt stress a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.252 0.057 response to salt stress a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.252 0.057 response to salt stress a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.243 0.057 response to salt stress a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.243 0.057 response to salt stress a.65.1 Annexin
View Download 0.241 0.057 response to salt stress d.54.1 Enolase N-terminal domain-like
View Download 0.241 0.057 response to salt stress d.201.1 SRP19
View Download 0.240 0.057 response to salt stress a.24.4 Hemerythrin
View Download 0.239 0.057 response to salt stress a.7.7 BAG domain
View Download 0.233 0.057 response to salt stress b.55.1 PH domain-like
View Download 0.233 0.057 response to salt stress a.24.3 Cytochromes
View Download 0.231 0.057 response to salt stress a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.216 0.057 response to salt stress a.118.8 TPR-like
View Download 0.216 0.057 response to salt stress a.4.3 ARID-like
View Download 0.216 0.057 response to salt stress a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.215 0.057 response to salt stress a.4.1 Homeodomain-like
View Download 0.214 0.057 response to salt stress a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.212 0.057 response to salt stress a.26.1 4-helical cytokines
View Download 0.210 0.057 response to salt stress a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.207 0.057 response to salt stress a.40.1 Calponin-homology domain, CH-domain
View Download 0.205 0.057 response to salt stress a.30.1 ROP protein
View Download 0.202 0.057 response to salt stress a.47.2 t-snare proteins
View Download 0.201 0.057 response to salt stress a.28.1 ACP-like

Predicted Domain #4
Region A:
Residues: [285-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKPARKIYST ALLTAQKLYW FKQSLGVKAS NEEFLSPISE ILSISLKWYA TQMKKFMDLS  60
   61 SPAFFSSEII LYSLPPKKQA KRLLENFHAT LLSSVTGIIS LKECLDLAEK YYSESGEKLT 120
  121 YPEHLLLNVC LCSGASATQS IIRGDSKFLR KDRYDPTSQE LKKIENVALL NAMYYYHKLS 180
  181 TICSGTRTLQ ALLLLNRYFQ LTYDTELANC ILGTAIRLAV DMELNRKSSY KSLDFEEAIR 240
  241 RRRMWWHCFC TDKLYSLMLS RPPIVGERDM DMLTDQNYYE VIKTNILPDL IDKKEDL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [582-806]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKITDVNSAL NVVVNFCQHI SLFISYYVSK LVSIESKIYS TCFAVRSTLD LSFDAMLDKI  60
   61 KDLNDSLNNW RDNLHVSMKL KSYKQYLSVL YAQKSQENPA LSFEIACSRV LNCHFRALYS 120
  121 KVILSMMTTS LLIDNERLYK GSRHDIPQLF ILFSSQYLNA SKEMLQLFQG INYQAHMYNE 180
  181 VMYQFSTAMF VLFFYVVDNM NDLKKKGEVK EIIDILKKSY DRLVG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [807-1030]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENDEQLLFDN VKWNTLIVFY SHFLKYVLQR YHALNDSTSI FDSKPYDETI TKVIMHSRKI  60
   61 KDETVDQLIM SLKSYGSLHS LQKGNEADLA DDGLNTNDIS SEDFAEEAPI NLFGELSVEI 120
  121 LKLLKSHSPI SNFGDLSPSS NRKGISDDSS LYPIRSDLTS LVYPIHSSDT GDTLSSGLET 180
  181 PENSNFNSDS GIKEDFEAFR ALLPLGKLIY DRDYSFVNTF RDYE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [849-1030]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKPYDETITK VIMHSRKIKD ETVDQLIMSL KSYGSLHSLQ KGNEADLADD GLNTNDISSE  60
   61 DFAEEAPINL FGELSVEILK LLKSHSPISN FGDLSPSSNR KGISDDSSLY PIRSDLTSLV 120
  121 YPIHSSDTGD TLSSGLETPE NSNFNSDSGI KEDFEAFRAL LPLGKLIYDR DYSFVNTFRD 180
  181 YE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle