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Protein Overview: PEX6

General Information:
Name(s) found: PEX6 / YNL329C [SGD]
Description(s) found:
Found 29 descriptions.
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  • AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1030 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [IDALink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]
    soluble fraction [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article][IMPLink to PubMed article]
    Biological Process: peroxisome organization [TAS]
    Molecular Function: ATPase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKASLTFSLS GIYAPCSISR DIYLEYGDKK AECLYGTIRL PQYGPGCTPG KIVHCVLDDS  60
   61 LPFCSIVVPS KLFGFMPTQP TMDFCYFEPI LDNVVPVLDS VTFLINEQLY SKLMDLPQEM 120
  121 QQIQFLHYKY NINSMETVVH SRDILTSGLC QILNCSPFPQ GLVDFTETQL ILVNDTEQKL 180
  181 SALKYANEDE EYALPKIGTN SALSIDLESL PCTISRDLLR PAPHINDDNS IYAFTDAETL 240
  241 LRLDVTSGSF ITVSNMGCVR LVKLFVLLLP NGFKKRTIYA PPKIIASFPD CSVVTISKSN 300
  301 IGHTDIPIAN QVFISRVGGW LQSQKCFQNI ILTTLKKFFS ESKRILCQND LIPIAFDSSM 360
  361 ADLNIAEEND ESDDEDELGQ YYKNDSLVWF FVTSAELDCF SKDNSHFIID PNRTKLITTN 420
  421 ITNRRPLPLS RSNLQRYYGF AETFYYDLHI FPYVRQLVNI LETSFNCSQR GITLNASVLL 480
  481 HSTTNNVGKA TMVRFASKYL GIHLLEIDCL SLTSNSRQLD STSKIIGYIR AKCENVLPYA 540
  541 SPAVIFLAHL DSILLDVNAN QDPEAIKLQK SINFEMSKLL DDFTFKFPGT TFVGSVNNID 600
  601 NVPSSFRSHM RFEILVPVPS EAQRLRIFQW YLSSHELNRD VQQKVPVSYM DNISFSSLSS 660
  661 YSAGLTPLDI KSIVETARMT ATARFYQESK KCGWLPQSIL ITQEDLSKAT SKARNEFSVS 720
  721 IGAPQIPNVT WDDIGGIDFV KGEILDTIDM PLKHPELFTS GMKKRSGILF YGPPGTGKTL 780
  781 MAKAIATNFS LNFFSVKGPE LLNMYIGESE ANVRRVFQKA REAKPCVIFF DEIDSVAPKR 840
  841 GNQGDSGGVM DRIVSQLLAE LDGMSTDADG VFVIGATNRP DLLDEALLRP GRFDKLLYLG 900
  901 IPDTDTKQLN ILEALTRKFV LDNDVKLIEL AKLCPFNYTG ADFYALCSDA MLNAMSRIAR 960
  961 MVEKKVSQHN ELTGENISTR RWFDKIATKE DTKVVVKMED FLKAQEQLTP SVSRAELNHY1020
 1021 EAVRANFEGA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) MDN1 PEX6 PIM1 USA1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen LSM4 PEX6 1 Unpublished Fields Lab Data
    View Screen PEX6 MCM21 1 Unpublished Fields Lab Data
    View Screen PEX6 PPZ2 1 Unpublished Fields Lab Data
    View Screen PEX6 GRH1 1 Unpublished Fields Lab Data
    View Screen PEX6 SPT4 1 Unpublished Fields Lab Data
    View Screen PEX6 YIR014W 1 Unpublished Fields Lab Data
    View Screen PEX6 RPA12 1 Unpublished Fields Lab Data
    View Screen PEX6 TVP38 1 Unpublished Fields Lab Data
    View Screen PEX6 YLR065C 1 Unpublished Fields Lab Data
    View Screen PEX6 SNF12 1 Unpublished Fields Lab Data
    View Screen PEX6 YAH1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PEX6 and PEX3 Huh WK, et al. (2003)
    View Data PEX6 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..190] deduced N/A No confident structure predictions are available.
    2 View Details [191..305] PSI-BLAST 593.457575 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    3 View Details [306..437] PSI-BLAST 593.457575 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    4 View Details [438..618] PSI-BLAST 593.457575 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    5 View Details [619..707] PSI-BLAST 593.457575 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    6 View Details [708..765] PSI-BLAST 5.522879 Replication factor C
    7 View Details [766..883] PSI-BLAST 5.39794 Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein
    8 View Details [884..1030] ORFEUS 14.61 AAA domain of cell division protein FtsH


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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