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Protein Overview: AQR1

General Information:
Name(s) found: AQR1 / YNL065W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 586 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDALink to PubMed article]
    Biological Process: drug transport [IMPLink to PubMed article]
    monocarboxylic acid transport [IMPLink to PubMed article]
    Molecular Function: drug transmembrane transporter activity [IMPLink to PubMed article]
    monocarboxylic acid transmembrane transporter activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSNSIYTE DIEMYPTHNE QHLTREYTKP DGQTKSEKLN FEGAYINSHG TLSKTTTREI  60
   61 EGDLDSETSS HSSDDKVDPT QQITAETKAP YTLLSYGQKW GMVAILTMCG FWSSLGSPIY 120
  121 YPALRQLEKQ FNVDENMVNV TVVVYLLFQG ISPTVSGGLA DCFGRRPIIL AGMLIYVIAS 180
  181 IGLACAPSYG VIIFLRCIQS IGISPTIAIS SGVVGDFTLK HERGTFVGAT SGFVLLGQCF 240
  241 GSLIGAVLTA RWDWRAIFWF LTIGCGSCFL IAFLILPETK RTIAGNLSIK PKRFINRAPI 300
  301 FLLGPVRRRF KYDNPDYETL DPTIPKLDLS SAGKILVLPE IILSLFPSGL LFAMWTLMLS 360
  361 SISSGLSVAP YNYHLVIIGV CYLPGGIGGL MGSFFTGRII DMYFKRKIKK FEQDKANGLI 420
  421 PQDAEINMFK VRLVCLLPQN FLAVVAYLLF GWSIDKGWRI ESILITSFVC SYCAMSTLST 480
  481 STTLLVDLYP TKSSTASSCF NFVRCSLSTI FMGCFAKMKA AMTVGGTFTF LCALVFFFNF 540
  541 LMFIPMKYGM KWREDRLLKQ QRQSWLNTLA VKAKKGTKRD QNDNHN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AQR1 CTF18 CTF8 DCC1
    View Details Qiu et al. (2008) AQR1 ATR1 BAP3 LYP1 QDR3 TAT1 TAT2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen EST1 AQR1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data AQR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..83] deduced N/A No confident structure predictions are available.
    2 View Details [84..277]
    [323..548]    		 PSI-BLAST 22.522879 No description for 1ja5A_ was found.
    3 View Details [278..322]
    [549..586]    		 PSI-BLAST 22.522879 No description for 1ja5A_ was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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