YRC Public Data Repository - Protein Structure Prediction

Protein:	AQR1
Organism:	Saccharomyces cerevisiae
Length:	586 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AQR1.

Description	E-value	Query Range	Subject Range
AQR1 - Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to sh... AQR1_YEAST - Probable transporter AQR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AQR1 PE=1 SV=1	0.0	[1..586]	[1..586]
YCT4_SCHPO - Uncharacterized transporter C794.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC7... SPCC794.04c - membrane transporter	3.0E-87	[41..562]	[50..547]
gi\|13702155, gi\|... - gi\|13702161\|dbj\|BAB43818.1\| CaNAG4 [Candida albicans], gi\|13702155\|dbj\|BAB43815.1\| CaNAG4 [Candida a... gi\|238882925 - gi\|238882925\|gb\|EEQ46563.1\| hypothetical protein CAWG_04919 [Candida albicans WO-1]	2.0E-81	[71..561]	[105..575]
gi\|5420310 - gi\|5420310\|emb\|CAB46647.1\| putative multiple drug resistance protein [Penicillium olsonii]	4.0E-81	[68..584]	[57..556]

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Predicted Domain #1

Region A:
Residues: [1-83]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSNSIYTE DIEMYPTHNE QHLTREYTKP DGQTKSEKLN FEGAYINSHG TLSKTTTREI  60
   61 EGDLDSETSS HSSDDKVDPT QQI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [84-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAETKAPYTL LSYGQKWGMV AILTMCGFWS SLGSPIYYPA LRQLEKQFNV DENMVNVTVV  60
   61 VYLLFQGISP TVSGGLADCF GRRPIILAGM LIYVIASIGL ACAPSYGVII FLRCIQSIGI 120
  121 SPTIAISSGV VGDFTLKHER GTFVGATSGF VLLGQCFGSL IGAVLTARWD WRAIFWFLTI 180
  181 GCGSCFLIAF LILP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [323-548]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIPKLDLSSA GKILVLPEII LSLFPSGLLF AMWTLMLSSI SSGLSVAPYN YHLVIIGVCY  60
   61 LPGGIGGLMG SFFTGRIIDM YFKRKIKKFE QDKANGLIPQ DAEINMFKVR LVCLLPQNFL 120
  121 AVVAYLLFGW SIDKGWRIES ILITSFVCSY CAMSTLSTST TLLVDLYPTK SSTASSCFNF 180
  181 VRCSLSTIFM GCFAKMKAAM TVGGTFTFLC ALVFFFNFLM FIPMKY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.522879
Match:	1ja5A_
Description:	No description for 1ja5A_ was found.

Predicted Domain #3

Region A:
Residues: [278-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETKRTIAGNL SIKPKRFINR APIFLLGPVR RRFKYDNPDY ETLDP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [549-586]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMKWREDRLL KQQRQSWLNT LAVKAKKGTK RDQNDNHN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.522879
Match:	1ja5A_
Description:	No description for 1ja5A_ was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits