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View Structure Prediction Details

Protein: AQR1
Organism: Saccharomyces cerevisiae
Length: 586 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AQR1.

Description E-value Query
Range
Subject
Range
AQR1 - Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to sh...
AQR1_YEAST - Probable transporter AQR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AQR1 PE=1 SV=1
0.0 [1..586] [1..586]
YCT4_SCHPO - Uncharacterized transporter C794.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC7...
SPCC794.04c - membrane transporter
3.0E-87 [41..562] [50..547]
gi|13702155, gi|... - gi|13702161|dbj|BAB43818.1| CaNAG4 [Candida albicans], gi|13702155|dbj|BAB43815.1| CaNAG4 [Candida a...
gi|238882925 - gi|238882925|gb|EEQ46563.1| hypothetical protein CAWG_04919 [Candida albicans WO-1]
2.0E-81 [71..561] [105..575]
gi|5420310 - gi|5420310|emb|CAB46647.1| putative multiple drug resistance protein [Penicillium olsonii]
4.0E-81 [68..584] [57..556]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSNSIYTE DIEMYPTHNE QHLTREYTKP DGQTKSEKLN FEGAYINSHG TLSKTTTREI  60
   61 EGDLDSETSS HSSDDKVDPT QQI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [84-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAETKAPYTL LSYGQKWGMV AILTMCGFWS SLGSPIYYPA LRQLEKQFNV DENMVNVTVV  60
   61 VYLLFQGISP TVSGGLADCF GRRPIILAGM LIYVIASIGL ACAPSYGVII FLRCIQSIGI 120
  121 SPTIAISSGV VGDFTLKHER GTFVGATSGF VLLGQCFGSL IGAVLTARWD WRAIFWFLTI 180
  181 GCGSCFLIAF LILP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [323-548]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIPKLDLSSA GKILVLPEII LSLFPSGLLF AMWTLMLSSI SSGLSVAPYN YHLVIIGVCY  60
   61 LPGGIGGLMG SFFTGRIIDM YFKRKIKKFE QDKANGLIPQ DAEINMFKVR LVCLLPQNFL 120
  121 AVVAYLLFGW SIDKGWRIES ILITSFVCSY CAMSTLSTST TLLVDLYPTK SSTASSCFNF 180
  181 VRCSLSTIFM GCFAKMKAAM TVGGTFTFLC ALVFFFNFLM FIPMKY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted Domain #3
Region A:
Residues: [278-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETKRTIAGNL SIKPKRFINR APIFLLGPVR RRFKYDNPDY ETLDP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [549-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMKWREDRLL KQQRQSWLNT LAVKAKKGTK RDQNDNHN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle