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View Structure Prediction Details

Protein: AQR1
Organism: Saccharomyces cerevisiae
Length: 586 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AQR1.

Description E-value Query
Range
Subject
Range
AQR1 - Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to sh...
AQR1_YEAST - Probable transporter AQR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AQR1 PE=1 SV=1
0.0 [1..586] [1..586]
YCT4_SCHPO - Uncharacterized transporter C794.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC7...
SPCC794.04c - membrane transporter
3.0E-87 [41..562] [50..547]
gi|13702155, gi|... - gi|13702161|dbj|BAB43818.1| CaNAG4 [Candida albicans], gi|13702155|dbj|BAB43815.1| CaNAG4 [Candida a...
gi|238882925 - gi|238882925|gb|EEQ46563.1| hypothetical protein CAWG_04919 [Candida albicans WO-1]
2.0E-81 [71..561] [105..575]
gi|5420310 - gi|5420310|emb|CAB46647.1| putative multiple drug resistance protein [Penicillium olsonii]
4.0E-81 [68..584] [57..556]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSNSIYTE DIEMYPTHNE QHLTREYTKP DGQTKSEKLN FEGAYINSHG TLSKTTTREI  60
   61 EGDLDSETSS HSSDDKVDPT QQI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.494 c.47.1 Thioredoxin-like
View Download 0.246 b.1.18 E set domains
View Download 0.356 b.11.1 gamma-Crystallin-like
View Download 0.275 a.40.1 Calponin-homology domain, CH-domain
View Download 0.494 c.47.1 Thioredoxin-like
View Download 0.356 b.11.1 gamma-Crystallin-like
View Download 0.316 d.72.1 Cyanase C-terminal domain
View Download 0.316 d.72.1 Cyanase C-terminal domain
View Download 0.275 a.40.1 Calponin-homology domain, CH-domain
View Download 0.246 b.1.18 E set domains
View Download 0.236 g.18.1 Complement control module/SCR domain
View Download 0.221 d.15.1 Ubiquitin-like

Predicted Domain #2
Region A:
Residues: [84-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAETKAPYTL LSYGQKWGMV AILTMCGFWS SLGSPIYYPA LRQLEKQFNV DENMVNVTVV  60
   61 VYLLFQGISP TVSGGLADCF GRRPIILAGM LIYVIASIGL ACAPSYGVII FLRCIQSIGI 120
  121 SPTIAISSGV VGDFTLKHER GTFVGATSGF VLLGQCFGSL IGAVLTARWD WRAIFWFLTI 180
  181 GCGSCFLIAF LILP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [323-548]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIPKLDLSSA GKILVLPEII LSLFPSGLLF AMWTLMLSSI SSGLSVAPYN YHLVIIGVCY  60
   61 LPGGIGGLMG SFFTGRIIDM YFKRKIKKFE QDKANGLIPQ DAEINMFKVR LVCLLPQNFL 120
  121 AVVAYLLFGW SIDKGWRIES ILITSFVCSY CAMSTLSTST TLLVDLYPTK SSTASSCFNF 180
  181 VRCSLSTIFM GCFAKMKAAM TVGGTFTFLC ALVFFFNFLM FIPMKY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted Domain #3
Region A:
Residues: [278-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETKRTIAGNL SIKPKRFINR APIFLLGPVR RRFKYDNPDY ETLDP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [549-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMKWREDRLL KQQRQSWLNT LAVKAKKGTK RDQNDNHN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle