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Protein Overview: SEN15

General Information:
Name(s) found: SEN15 / YMR059W [SGD]
Description(s) found:
Found 15 descriptions.
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  • Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 148 amino acids

    Gene Ontology:
    Cellular Component: nuclear inner membrane [TASLink to PubMed article]
    tRNA-intron endonuclease complex [TASLink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    Biological Process: tRNA splicing, via endonucleolytic cleavage and ligation [TASLink to PubMed article]
    Molecular Function: tRNA-intron endonuclease activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDIINCRRE ITSRRLRKIR MATTDIISLV KNNLLYFQMW TEVEILQDDL SWKGNSLRLL  60
   61 RGRPPHKLSN DVDTEHENSL SSPRPLEFIL PINMSQYKEN FLTLECLSQT FTHLCSPSTE 120
  121 RILLAIINDD GTIVYYFVYK GVRKPKRN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AI2 SEN15 SEN2 SEN34 SEN54 TRL1 TRM1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle