Protein Overview: SEN15

General Information:
Name(s) found:	SEN15 / YMR059W [SGD]
Description(s) found: Found 15 descriptions. SHOW ALL	Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	148 amino acids
Gene Ontology:
Cellular Component:	nuclear inner membrane [TAS] tRNA-intron endonuclease complex [TAS] mitochondrial outer membrane [IDA][IMP][IPI]
Biological Process:	tRNA splicing, via endonucleolytic cleavage and ligation [TAS]
Molecular Function:	tRNA-intron endonuclease activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDIINCRRE ITSRRLRKIR MATTDIISLV KNNLLYFQMW TEVEILQDDL SWKGNSLRLL  60
   61 RGRPPHKLSN DVDTEHENSL SSPRPLEFIL PINMSQYKEN FLTLECLSQT FTHLCSPSTE 120
  121 RILLAIINDD GTIVYYFVYK GVRKPKRN

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		AI2 SEN15 SEN2 SEN34 SEN54 TRL1 TRM1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	HMT1	SEN15	1	Unpublished Fields Lab Data
View Screen	SEN15	YHL049C	1	Unpublished Fields Lab Data
View Screen	RPC19	SEN15	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..148]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.84

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2