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Protein Overview: MSC1

General Information:
Name(s) found: MSC1 / YML128C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 513 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: reciprocal meiotic recombination [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQFKLVNAV SASFVLIGLV LANSDSVFDK WTQEDLADYL RDNKKSLEKY ATDSIEDLKT  60
   61 EASQVWDKHA QPKPWWQVWS SDSSSVSNSN PGWFGYTGSS DHPVSDWLFD TWSTDSLRNF 120
  121 LKKNGVDVDD AKASKDSLVK TAKENFNKIS KSLKSSGYYP SSSYFDSWST KDLQNWLNDN 180
  181 GIDYDKAVQS KDELVQKVKE NIYRTSEKAE QQRLGLLESL DLAHQQILDT SGQIKDTVFD 240
  241 KWSSDQLTNW LESHKVNIDK NMAKKHDYLV RMAKENSANL KDDIYWYLDY MKRESSPFLT 300
  301 KTPEYVGSVW DSSKNFLTNL YSKFRGKTDN VINDTFLVGL DSWPKDKLKM FLDARGIKYS 360
  361 MLSTEHQLRE LVKKSRNEKL KILPKDYQKY FDNSNWSLDD IKGWFADKKD DFQDSQTYST 420
  421 IMQDFDKVSK NTNDAKDQIA KTWSNTFQSW SQEDLLQYLK SFGVPVKQTS TKDDLINLAK 480
  481 QNTQWLFGTV KEPAYKRYLH NVKNWSKSIL GFN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MSC1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..395] MSA 38.100997 View MSA. No confident structure predictions are available.
    2 View Details [396..513] deduced N/A No confident structure predictions are available.
    3 View Details [330..513] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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