YRC Public Data Repository - Protein Structure Prediction

Protein:	MSC1
Organism:	Saccharomyces cerevisiae
Length:	513 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSC1.

Description	E-value	Query Range	Subject Range
MSC1_YEAST - Meiotic sister chromatid recombination protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S... MSC1 - Protein of unknown function; mutant is defective in directing meiotic recombination events to homolo...	0.0	[1..513]	[1..513]
gi\|1790878, gi\|1... - gi\|1790880\|gb\|AAB41133.1\| microtubule-associated protein 1a [Homo sapiens], gi\|1790878\|gb\|AAB41132.1...	1.0E-40	[21..299]	[1316..1610]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-30	[18..336]	[755..1032]
gi\|25406145, gi\|... - pir\|\|C96744 hypothetical protein F28P5.13 [imported] - Arabidopsis thaliana, gi\|15218349\|ref\|NP_177...	5.0E-29	[53..319]	[51..295]
gi\|25401636 - pir\|\|D86798 prophage pi3 protein 14 [imported] - Lactococcus lactis subsp. lactis (strain IL1403) gi\|12830984, gi\|... - gi\|13095795\|ref\|NP_076686.1\| tail protein [Lactococcus phage bIL286], gi\|12830984\|gb\|AAK08339.1\|AF32... gi\|15673370, gi\|... - gi\|15673370\|ref\|NP_267544.1\| prophage pi3 protein 14 [Lactococcus lactis subsp. lactis Il1403], gi\|1...	1.0E-28	[48..330]	[934..1208]

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Predicted Domain #1

Region A:
Residues: [1-395]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQFKLVNAV SASFVLIGLV LANSDSVFDK WTQEDLADYL RDNKKSLEKY ATDSIEDLKT  60
   61 EASQVWDKHA QPKPWWQVWS SDSSSVSNSN PGWFGYTGSS DHPVSDWLFD TWSTDSLRNF 120
  121 LKKNGVDVDD AKASKDSLVK TAKENFNKIS KSLKSSGYYP SSSYFDSWST KDLQNWLNDN 180
  181 GIDYDKAVQS KDELVQKVKE NIYRTSEKAE QQRLGLLESL DLAHQQILDT SGQIKDTVFD 240
  241 KWSSDQLTNW LESHKVNIDK NMAKKHDYLV RMAKENSANL KDDIYWYLDY MKRESSPFLT 300
  301 KTPEYVGSVW DSSKNFLTNL YSKFRGKTDN VINDTFLVGL DSWPKDKLKM FLDARGIKYS 360
  361 MLSTEHQLRE LVKKSRNEKL KILPKDYQKY FDNSN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [396-513]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WSLDDIKGWF ADKKDDFQDS QTYSTIMQDF DKVSKNTNDA KDQIAKTWSN TFQSWSQEDL  60
   61 LQYLKSFGVP VKQTSTKDDL INLAKQNTQW LFGTVKEPAY KRYLHNVKNW SKSILGFN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [330-513]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVINDTFLVG LDSWPKDKLK MFLDARGIKY SMLSTEHQLR ELVKKSRNEK LKILPKDYQK  60
   61 YFDNSNWSLD DIKGWFADKK DDFQDSQTYS TIMQDFDKVS KNTNDAKDQI AKTWSNTFQS 120
  121 WSQEDLLQYL KSFGVPVKQT STKDDLINLA KQNTQWLFGT VKEPAYKRYL HNVKNWSKSI 180
  181 LGFN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits