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Protein Overview: RNH203

General Information:
Name(s) found: RNH203 / YLR154C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Ribonuclease H2 subunit, required for RNase H2 activity; related to human AGS3 that causes Aicardi-Goutieres syndrome [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 110 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    ribonuclease H2 complex [IDALink to PubMed article]
    Biological Process: DNA replication [IPILink to PubMed article]
    Molecular Function: ribonuclease H activity [IDALink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKDAVNLDA YTVSFMPFYT EYQGPTEEFK DYKFEDTIYF RGKELKREKS ATPSSSDNTT  60
   61 SNTFSNGAIL SGNTITGKIV SVNNYEREGT DRNELARLQE LISLIDVINQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) RNH201 RNH202 RNH203
    View Details Ho Y, et al. (2002) BCK2 BEM3 CKA2 CKB1 DIG1 DUN1 KSS1 RNH203 RVB1 STE11 STE12 STE7 TOP2
    View Details Qiu et al. (2008) RNH201 RNH202 RNH203

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RNH203 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..110] Pfam 19.275724 No description for PF08615.2 was found. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle