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Protein Overview: YLR143W

General Information:
Name(s) found: YLR143W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Putative protein of unknown function; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; YLR143W is not an essential gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 685 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFIALISGG KDSFYNIFHC LKNNHELIAL GNIYPKESEE QELDSFMFQT VGHDLIDYYS  60
   61 KCIGVPLFRR SILRNTSNNV ELNYTATQDD EIEELFELLR TVKDKIPDLE AVSVGAILSS 120
  121 YQRTRVENVC SRLGLVVLSY LWQRDQAELM GEMCLMSKDV NNVENDTNSG NKFDARIIKV 180
  181 AAIGLNEKHL GMSLPMMQPV LQKLNQLYQV HICGEGGEFE TMVLDAPFFQ HGYLELIDIV 240
  241 KCSDGEVHNA RLKVKFQPRN LSKSFLLNQL DQLPVPSIFG NNWQDLTQNL PKQQAKTGEQ 300
  301 RFENHMSNAL PQTTINKTND KLYISNLQSR KSETVEKQSE DIFTELADIL HSNQIPRNHI 360
  361 LSASLLIRDM SNFGKINKIY NEFLDLSKYG PLPPSRACVG SKCLPEDCHV QLSVVVDVKN 420
  421 TGKEKINKNK GGLHVQGRSY WAPCNIGPYS QSTWLNDDAN QVSFISGQIG LVPQSMEILG 480
  481 TPLTDQIVLA LQHFDTLCET IGAQEKLLMT CYISDESVLD SVIKTWAFYC SNMNHRSDLW 540
  541 MDKSDDVEKC LVLVKISELP RGAVAEFGGV TCKRLIVDDN DSDKKEREEN DDVSTVFQKL 600
  601 NLNIEGFHNT TVSAFGYNRN FITGFVDSRE ELELILEKTP KSAQITLYYN PKEIITFHHH 660
  661 IGYYPVEKLF DYRGKEHRFG LHIRS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ALD2 ALD3 YLR143W YPF1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YLR143W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] ORFEUS 13.59 Argininosuccinate synthetase, N-terminal domain; Argininosuccinate synthetase, C-terminal domain
    2 View Details [160..279] Pfam 11.275724 ATP-binding region No confident structure predictions are available.
    3 View Details [280..426] PSI-BLAST 102.751666 Purine regulatory protein YabJ
    4 View Details [427..587] MSA 28.15299 View MSA. No confident structure predictions are available.
    5 View Details [588..685] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity
    		•  2.99185607397345 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.14663773925119 bayes_pls_golite062009
  • DNA binding
    		•  0.992954560970173 bayes_pls_golite062009
  • catalytic activity
    		•  0.828867994386867 bayes_pls_golite062009
  • binding
    		•  0.752095595503409 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • ribonuclease activity
    		•  2.55513289511254 bayes_pls_golite062009
  • nuclease activity
    		•  1.95684086528131 bayes_pls_golite062009
  • endonuclease activity
    		•  1.93161199243014 bayes_pls_golite062009
  • binding
    		•  1.28584712198396 bayes_pls_golite062009
  • endoribonuclease activity
    		•  1.18839679198466 bayes_pls_golite062009
  • catalytic activity
    		•  1.00848565859536 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.659253495197665 bayes_pls_golite062009
  • hydrolase activity
    		•  0.213547115506972 bayes_pls_golite062009
  • protein binding
    		•  0.126122948490201 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle