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Protein Overview: PML1

General Information:
Name(s) found: PML1 / YLR016C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Subunit of the RES complex, which is required for nuclear retention of unspliced pre-mRNAs; acts in the same pathway as Pml39p and Mlp1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 204 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: mRNA export from nucleus [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    nuclear mRNA splicing, via spliceosome [IDALink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFHRRKRPYN TRNYGHDDKK FKSQYIDIMP DFSPSGLLEL ESNNKEGIAL KHVEPQDAIS  60
   61 PDNYMDMLGL EARDRTMYEL VIYRKNDKDK GPWKRYDLNG RSCYLVGREL GHSLDTDLDD 120
  121 RTEIVVADIG IPEETSSKQH CVIQFRNVRG ILKCYVMDLD SSNGTCLNNV VIPGARYIEL 180
  181 RSGDVLTLSE FEEDNDYELI FMNV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) BUD13 ILS1 PML1 SMC4 SRP1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PML1 CTP1 2 Unpublished Fields Lab Data
    View Screen PML1 TIM22 2 Unpublished Fields Lab Data
    View Screen PML1 RNP1 2 Unpublished Fields Lab Data
    View Screen PML1 RTT106 2 Unpublished Fields Lab Data
    View Screen PML1 URE2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PML1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..72] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [73..204] PSI-BLAST 8.221849 Cell cycle checkpoint protein Chfr


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle