YRC Public Data Repository - Protein Structure Prediction

Protein:	PML1
Organism:	Saccharomyces cerevisiae
Length:	204 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PML1.

Description	E-value	Query Range	Subject Range
PML1_YEAST - Pre-mRNA leakage protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PML1 PE=1 SV=... gi\|151941184 - gi\|151941184\|gb\|EDN59562.1\| Pre-mRNA Leakage [Saccharomyces cerevisiae YJM789] gi\|190406057 - gi\|190406057\|gb\|EDV09324.1\| pre-mRNA leakage protein 1 [Saccharomyces cerevisiae RM11-1a] gi\|207343202 - gi\|207343202\|gb\|EDZ70737.1\| YLR016Cp-like protein [Saccharomyces cerevisiae AWRI1631] PML1 - Subunit of the RES complex, which is required for nuclear retention of unspliced pre-mRNAs; acts in ...	6.0E-62	[1..204]	[1..204]
DDL_ARATH - FHA domain-containing protein DDL OS=Arabidopsis thaliana GN=DDL PE=1 SV=1	5.0E-35	[28..203]	[159..311]
gi\|208967428 - gi\|208967428\|dbj\|BAG73728.1\| Smad nuclear interacting protein 1 [synthetic construct] SNIP1 - Smad nuclear interacting protein 1	7.0E-30	[28..202]	[222..372]
CE08529 - status:Confirmed UniProt:P91125 protein_id:AAB42323.1	5.0E-29	[28..189]	[129..268]
ODHI_CORGL - Oxoglutarate dehydrogenase inhibitor OS=Corynebacterium glutamicum GN=odhI PE=1 SV=1 gi\|145295574, gi... - gi\|145295574\|ref\|YP_001138395.1\| hypothetical protein cgR_1501 [Corynebacterium glutamicum R], gi\|14... ODHI_CORGL - Oxoglutarate dehydrogenase inhibitor OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / ...	6.0E-21	[40..193]	[13..135]
gi\|12060475 - gi\|12060475\|dbj\|BAB20624.1\| adenylate cyclase [Thermosynechococcus elongatus] gi\|22299953, gi\|... - gi\|22299953\|ref\|NP_683200.1\| adenylate cyclase [Thermosynechococcus elongatus BP-1], gi\|22296138\|dbj...	1.0E-20	[68..194]	[61..162]

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Predicted Domain #1

Region A:
Residues: [1-72]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFHRRKRPYN TRNYGHDDKK FKSQYIDIMP DFSPSGLLEL ESNNKEGIAL KHVEPQDAIS  60
   61 PDNYMDMLGL EA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.802	0.027	cytoplasm	d.58.17	Metal-binding domain

Predicted Domain #2

Region A:
Residues: [73-204]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDRTMYELVI YRKNDKDKGP WKRYDLNGRS CYLVGRELGH SLDTDLDDRT EIVVADIGIP  60
   61 EETSSKQHCV IQFRNVRGIL KCYVMDLDSS NGTCLNNVVI PGARYIELRS GDVLTLSEFE 120
  121 EDNDYELIFM NV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.221849
Match:	1lgqA_
Description:	Cell cycle checkpoint protein Chfr
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits