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Protein Overview: VPS70

General Information:
Name(s) found: VPS70 / YJR126C [SGD]
Description(s) found:
Found 26 descriptions.
SHOW ALL
  • Protein of unknown function involved in vacuolar protein sorting [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 811 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: protein targeting to vacuole [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRMIQRERKR EKEEGQLKER TVVNMADPDD NEAEATGLQQ YSGETTRDDN EESMNDSFTL  60
   61 TSRNRGRSNT ISSIVSGYEI MKEHMDKEKF MYLILASLLL YMGFVAAFAP RTSLSRDFRR 120
  121 FHSSRLTNAE VYRIYLNSLQ QENRAKEHVY KYAGYMSNGA SDSSTFKYTL DEFLDMGYKP 180
  181 KVEKYYPWIG EPVDTNVAPL ENGKVVYEAS MIEDRVKGDP ASHARKRQKG FHQYSKNGSV 240
  241 TARYVFCNYG SISDYKLLLK KNIDIEDKIH IVRSGKILPG LKVKNAELYG ASSVIIYTDP 300
  301 FDDGKVTEEN GFLHYPYGPA RNPSYIRRDS VNYFSDTPGD PTTPGYPSKD SDTEHMSPVG 360
  361 RVPRIPSVPM SARDVQPILE RLNGRGFQIG PGSNIKDFGS FTGPSSSIDK VHLHNELTYN 420
  421 IKEMSSVEVS IPGIFTEGEI IIGAHRDSLA SSSAGDANSG SAILLEIARG MSKLLKHGWK 480
  481 PLRPIKLISW DGERSGLLGS TDYAEAHAAI LRRRALVYLN LDNAISGTNF HCKANPLLQD 540
  541 VIYEAAKLTE FNGHEDWSLF DHWKYTSNAT ISLLDGLSSY TSFQYHLGVP AAHFQFNAND 600
  601 TSGAVYHSNS VFDSPTWLEK FTNSDYKLHN TMAMFVGLTT LMLSENELAR FNTHVYLKKI 660
  661 YNWYIAWHSN LSSAFPQDDE VNSLAKRVLD LLKVATQEDS IQFDQQNGIL YKECREALPV 720
  721 WAFYKKIKSY IKLQRSNSKS KQIDQLFITH RGLKDREWMK YSLLAPSKFE GSVGEVLPGL 780
  781 HEGLADIDRN EVIQWLTILL SQFSNVRYLL Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..124] deduced N/A No confident structure predictions are available.
    2 View Details [125..215]
    [335..361]
    [419..652]    		 PSI-BLAST 359.9897 Transferrin receptor ectodomain, C-terminal domain; Transferrin receptor ectodomain, apical domain; Transferrin receptor ectodomain, protease-like domain
    3 View Details [216..334]
    [362..418]
    [653..811]    		 PSI-BLAST 359.9897 Transferrin receptor ectodomain, C-terminal domain; Transferrin receptor ectodomain, apical domain; Transferrin receptor ectodomain, protease-like domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  3.33010352069253 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.96046345079997 bayes_pls_golite062009
  • hydrolase activity
    		•  2.61327242243519 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.70361627875478 bayes_pls_golite062009
  • catalytic activity
    		•  1.3989281287879 bayes_pls_golite062009
  • metallopeptidase activity
    		•  1.34087538226325 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  0.891655769761122 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  0.619120257877893 bayes_pls_golite062009
  • signal transducer activity
    		•  0.267328041739913 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.267328041739913 bayes_pls_golite062009
  • binding
    		•  0.228948932725967 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  0.180859448845431 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.137810390418952 bayes_pls_golite062009
  • receptor activity
    		•  0.0721997980843692 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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