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Protein Overview: MTC1

General Information:
Name(s) found: MTC1 / YJL123C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); mtc1 is synthetically lethal with cdc13-1 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 478 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    ribosome [IDALink to PubMed article]
    COPI-coated vesicle [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSENKNSEAE DVFEFLDSLP EAKNGGKMVN TDVKGSQEGV KGGSNSVAGK TGNDGKKGDD  60
   61 DIFEFLEELE KSNLSLTDKK GVEKKAPSES VNNKAQDEKV EESKENKNSE QDAHGKEKEP 120
  121 QQQEKEEEEE EEEEEEEEEE ETPLHDPIAS ISNWWSSSGS AKVSSIWNKT AEQASQIKNR 180
  181 LAQEQLDLTS KINTSTITEI ARNLQKIVVG ETEEVLRIHL VHDLVNYPSL QYNIESKFDQ 240
  241 VLSSQVEGGI RIFVDEWGHP NNNGITPVEK KPSVADGELG NSKKKLQFNL FDGKVTDGEK 300
  301 LAFANLENAV KLFNTAHEEY QKQQKEADAT PDDDRSSISS NSNKISDLFI SILPIAIPQK 360
  361 QKDADGDFQV TDSNTPGNFN FTLVLKDITN DITTITRSQG FPVKWVNWLE GSVEKTGSTA 420
  421 SEERNKSYDQ KKQKESEDED EDDEIIDPSE WVKEWIEDGL SLSFGVMAQN YVIDRMGL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) IFA38 MTC1
    View Details Gavin AC, et al. (2006) BBC1 MTC1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MTC1 and ANP1 Huh WK, et al. (2003)
    View Data MTC1 and COP1 Huh WK, et al. (2003)
    View Data MTC1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..267] ORFEUS 14.56 No description for 1ldvA was found.
    2 View Details [268..478] deduced N/A No confident structure predictions are available.
    3 View Details [266..478] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle