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Protein Overview: PAM16

General Information:
Name(s) found: PAM16 / YJL104W [SGD]
Description(s) found:
Found 33 descriptions.
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  • Constituent of the import motor (PAM complex) component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains a J-like domain [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 149 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial inner membrane presequence translocase complex [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    presequence translocase-associated import motor [IDALink to PubMed article]
    Biological Process: protein import into mitochondrial matrix [IMPLink to PubMed articleLink to PubMed article][IPILink to PubMed articleLink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed articleLink to PubMed article]
    enzyme inhibitor activity [IDALink to PubMed article]
    protein transporter activity [IMPLink to PubMed articleLink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHRAFIQVI ITGTQVFGKA FAEAYRQAAS QSVKQGATNA SRRGTGKGEY GGITLDESCK  60
   61 ILNIEESKGD LNMDKINNRF NYLFEVNDKE KGGSFYLQSK VYRAAERLKW ELAQREKNAK 120
  121 AKAGDASTAK PPPNSTNSSG ADNSASSNQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) MDJ2 MGE1 PAM16 PAM17 PAM18 SSC1 TIM17 TIM23 TIM44 TIM50 TIM54 TOM20 TOM6

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data PAM16 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..149] ORFEUS 10.75 Large T antigen, the N-terminal J domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.99176821643352 bayes_pls_golite062009
  • protein binding
    		•  1.51948307385917 bayes_pls_golite062009
  • transporter activity
    		•  1.30714426711368 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.819666949578493 bayes_pls_golite062009
  • unfolded protein binding
    		•  0.59395300664956 bayes_pls_golite062009
  • heat shock protein binding
    		•  0.335529947375073 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle