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Protein Overview: TIM17

General Information:
Name(s) found: TIM17 / YJL143W [SGD]
Description(s) found:
Found 32 descriptions.
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  • Essential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); with Tim23p, contributes to the architecture and function of the import channel; may link the import motor to the core TIM23 complex [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 158 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial inner membrane presequence translocase complex [IDALink to PubMed article][TASLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: protein import into mitochondrial matrix [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: protein transporter activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSADHSRDPC PIVILNDFGG AFAMGAIGGV VWHGIKGFRN SPLGERGSGA MSAIKARAPV  60
   61 LGGNFGVWGG LFSTFDCAVK AVRKREDPWN AIIAGFFTGG ALAVRGGWRH TRNSSITCAC 120
  121 LLGVIEGVGL MFQRYAAWQA KPMAPPLPEA PSSQPLQA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) TIM17 TIM23
    View Details Qiu et al. (2008) MDJ2 MGE1 PAM16 PAM18 TIM17 TIM23 TIM44 TIM50 TOM20 TOM22 TOM5

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TIM17 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..158] Pfam 81.721246 Tim17/Tim22/Tim23 family No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle