Protein Overview: SIP4

General Information:
Name(s) found:	SIP4 / YJL089W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|929865\|emb\|CAA58479.1\| J0922 [Saccharomyces cerevisiae] [NCBI NR] gi\|6322372\|ref\|NP_012446.1\| C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to [NCBI NR] gi\|1173439\|sp\|P46954.1\|SIP4_YEAST RecName: Full=Protein SIP4 [NCBI NR] gi\|1008258\|emb\|CAA89382.1\| SIP4 [Saccharomyces cerevisiae] [NCBI NR] Protein SIP4 OS=Saccharomyces cerevisiae GN=SIP4 PE=2 SV=1 [Swiss-Prot] SIP4 Interacts with SNF1 protein kinase [mips] C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus [SGD] SIP4, Chr X from 265622-268111 [yeast_orfs2] Chr X from 265622-268111 [yeastorf3.fasta] (P46954) SIP4 protein [4932.FASTACCERV.txt] SIP4 SGDID:S0003625, Chr X from 265842-268331, Verified ORF [yeastflysequest.fasta] Possibly involved in Snf1p regulated transcriptional activation; shows homology to DNA binding domain of Gal4p, has a leucine zipper motif and acidic region; lexA-Sip4p activates transcription [Saccharomyces cerevisiae]gi\|1008258\|emb\|CAA89382.1\| SIP4 [Sa [nrdb_11152004_Chlamydomonas] SIP4 SGDID:S000003625, Chr X from 265842-268331, Verified ORF, "C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated b [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] SIP4 SGDID:S000003625, Chr X from 265921-268410, Verified ORF, "C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated b [yeast-contam.fasta] SIP4 SGDID:S000003625, Chr X from 265920-268409, Verified ORF, "C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated b [yeast-200209-contam.fasta] J0922 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein SIP4 [nr-271106-contam.fasta] SIP4 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus; Sip4p [Sacchar [nr-271106-contam.fasta] SIP4 SGDID:S000003625, Chr X from 265920-268409, Verified ORF, "C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus" [yeast-bovrabprots.fasta] SIP4 SGDID:S000003625, Chr X from 265921-268410, Verified ORF, "C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus" [yeast-contam_custom.fasta] [chemostatdb.fasta] Protein SIP4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIP4 PE=2 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SIP4 SGDID:S000003625, Chr X from 265926-268415, Genome Release 64-1-1, Verified ORF, "C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus" [yeast-030211-contam.fasta] Protein SIP4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIP4 PE=4 SV=1 [YEAST.fasta.20131015] SIP4 SGDID:S000003625, Chr X from 265926-268415, Genome Release 64-2-1, Verified ORF, "C6 zinc cluster transcriptional activator; binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus" [20141208_orf_trans.fasta] YJL089W SGDID:S000003625, Chr X from 265926-268415, Genome Release 64-1-1, Verified ORF, "C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] Protein SIP4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIP4 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Saccharomyces cerevisiae
Length:	829 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	invasive growth in response to glucose limitation [IMP] positive regulation of gluconeogenesis [IMP][IPI] regulation of transcription from RNA polymerase II promoter [IMP][IPI]
Molecular Function:	specific RNA polymerase II transcription factor activity [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKRKYGRSY SLDDTDSCSN KVLIVPTGQS SSNAITDFSV RKAHACDRCR LKKIKCDGLK  60
   61 PNCSNCAKID FPCKTSDKLS RRGLPKGYTE LLEKEVVRLT NMNASSSANA NSNLPFINDT 120
  121 FYCFDNYNTQ SENQRFLGHL TWNILTNTFP TQKAVVFTDD RNNIDLQLQL LTNFLNLNGD 180
  181 FNHLPNFLLL KYDYNLQFLK NLLSVIIKDF FKRQNSLLLL LYPTNLWKNL LLDKINSTAM 240
  241 TGEPITLLAL LYIIQFTWSC FDDFKLFKVT KLIVSLTTNS KLDLKVLQLV NLSIFYFMGA 300
  301 SVDSCKSKSS LTEHSNVNSV IWTNDLLNLN FTNILNMGLY INPKNLIPIS GNNNNNKSNE 360
  361 EDDRIVTFWC FQFLSSWWSL IQGLPKSNFL TEEFQPKSIS VLEIPRLKPF EILLNFIIYS 420
  421 LDGCNLLNIS SLNVSDPNFQ FFQNELESFK KNLLLWNLYH NLSDHDNFRF LTSSSNKKLT 480
  481 TNLLLKNLTG LNHKLNQPDF VEIQLTLFYL SLKLMTLKEG DQDLKKEDIS LEILSLYFLI 540
  541 LTDDSNNDDN QQLQPQQLNL YHFTPFNSID IIDLCLNNLN NWSLSLKYES GQNQPHSSKI 600
  601 KFEKFQNFLN HWCPIWYYDE FSTNPFLQIL KINFKLLPFE TIHYSQEEQR LLISLNKLRY 660
  661 LDAVSSFNSS SVKSNFASKV NTQLNLLQHS SSNSNFLDAS PYDFNKIFMN NFENYDYETD 720
  721 EGYAEDDDEE DSDSDNSLPL EIPFKKSKNK CKNRNKELSQ RLSLFENRDS NSVDFNTDTN 780
  781 LNLNPDSPSV TSSKKKYLDH IILDNRDIVS NHDSSKQKFK IQNILNSTF

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		GAL83 SIP1 SIP2 SIP4 SNF1 SNF4
View Details	Qiu et al. (2008)		CAT8 GAL83 SIP1 SIP2 SIP4

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..176]	PSI-BLAST	105.30103	PPR1
2	View Details	[177..829]	deduced	N/A	No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: SIP4

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: