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Protein Overview: ARG3

General Information:
Name(s) found: ARG3 / YJL088W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 338 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: arginine biosynthetic process [TASLink to PubMed article]
    ornithine metabolic process [TASLink to PubMed article]
    Molecular Function: ornithine carbamoyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTASTPSS LRHLISIKDL SDEEFRILVQ RAQHFKNVFK ANKTNDFQSN HLKLLGRTIA  60
   61 LIFTKRSTRT RISTEGAATF FGAQPMFLGK EDIQLGVNES FYDTTKVVSS MVSCIFARVN 120
  121 KHEDILAFCK DSSVPIINSL CDKFHPLQAI CDLLTIIENF NISLDEVNKG INSKLKMAWI 180
  181 GDANNVINDM CIACLKFGIS VSISTPPGIE MDSDIVDEAK KVAERNGATF ELTHDSLKAS 240
  241 TNANILVTDT FVSMGEEFAK QAKLKQFKGF QINQELVSVA DPNYKFMHCL PRHQEEVSDD 300
  301 VFYGEHSIVF EEAENRLYAA MSAIDIFVNN KGNFKDLK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ARG3 ATP3 BUD30 CIK1 GAL80 PMI40 SGN1 YGR250C YML002W YOR1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run NOP9 No Comments Hazbun TR, et al. (2003)
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ARG3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..338] PSI-BLAST 115.0 Refined Structure of Pyrococcus furiosus Ornithine Carbamoyltransferase at 1.87 A

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ornithine carbamoyltransferase activity
    		•  6.08861672645671 bayes_pls_golite062009
  • carboxyl- or carbamoyltransferase activity
    		•  5.32518877756022 bayes_pls_golite062009
  • aspartate carbamoyltransferase activity
    		•  3.84118892938517 bayes_pls_golite062009
  • transferase activity
    		•  2.2887439598954 bayes_pls_golite062009
  • carbamoyl-phosphate synthase activity
    		•  2.21516900257798 bayes_pls_golite062009
  • carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
    		•  2.19154218663721 bayes_pls_golite062009
  • catalytic activity
    		•  2.06069688716378 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  1.54712264845123 bayes_pls_golite062009
  • binding
    		•  1.00470116390248 bayes_pls_golite062009
  • dihydroorotase activity
    		•  0.585784960037124 bayes_pls_golite062009
  • protein binding
    		•  0.171217252293449 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle