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View Structure Prediction Details

Protein: ARG3
Organism: Saccharomyces cerevisiae
Length: 338 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARG3.

Description E-value Query
Range
Subject
Range
OTC_PYRAB - Ornithine carbamoyltransferase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=argF PE=3 SV=4
OTC_PYRAB - Ornithine carbamoyltransferase OS=Pyrococcus abyssi GN=argF PE=3 SV=4
0.0 [5..330] [1..312]
OTC_PYRHO - Ornithine carbamoyltransferase OS=Pyrococcus horikoshii GN=argF PE=3 SV=3
OTC_PYRHO - Ornithine carbamoyltransferase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 /...
0.0 [5..330] [1..312]
OTC_PYRFU - Ornithine carbamoyltransferase OS=Pyrococcus furiosus GN=argF PE=1 SV=6
OTC_PYRFU - Ornithine carbamoyltransferase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1...
0.0 [5..330] [1..312]
OTC_PYRFU - (Q51742) Ornithine carbamoyltransferase (EC 2.1.3.3) (OTCase)
0.0 [8..330] [3..311]
OTC_BACSU - Ornithine carbamoyltransferase OS=Bacillus subtilis (strain 168) GN=argF PE=1 SV=1
gi|221322488 - gi|221322488|ref|ZP_03603782.1| ornithine carbamoyltransferase [Bacillus subtilis subsp. subtilis st...
gi|221318214 - gi|221318214|ref|ZP_03599508.1| ornithine carbamoyltransferase [Bacillus subtilis subsp. subtilis st...
gi|221313290 - gi|221313290|ref|ZP_03595095.1| ornithine carbamoyltransferase [Bacillus subtilis subsp. subtilis st...
OTC_BACSU - Ornithine carbamoyltransferase OS=Bacillus subtilis GN=argF PE=1 SV=1
0.0 [1..328] [1..310]
OTC_BACHD - Ornithine carbamoyltransferase OS=Bacillus halodurans GN=argF PE=3 SV=1
OTC_BACHD - Ornithine carbamoyltransferase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 /...
0.0 [8..331] [10..319]
OTC_GEOSL - Ornithine carbamoyltransferase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=...
OTC_GEOSL - Ornithine carbamoyltransferase OS=Geobacter sulfurreducens GN=argF PE=3 SV=1
0.0 [12..328] [3..302]

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Predicted Domain #1
Region A:
Residues: [1-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTASTPSS LRHLISIKDL SDEEFRILVQ RAQHFKNVFK ANKTNDFQSN HLKLLGRTIA  60
   61 LIFTKRSTRT RISTEGAATF FGAQPMFLGK EDIQLGVNES FYDTTKVVSS MVSCIFARVN 120
  121 KHEDILAFCK DSSVPIINSL CDKFHPLQAI CDLLTIIENF NISLDEVNKG INSKLKMAWI 180
  181 GDANNVINDM CIACLKFGIS VSISTPPGIE MDSDIVDEAK KVAERNGATF ELTHDSLKAS 240
  241 TNANILVTDT FVSMGEEFAK QAKLKQFKGF QINQELVSVA DPNYKFMHCL PRHQEEVSDD 300
  301 VFYGEHSIVF EEAENRLYAA MSAIDIFVNN KGNFKDLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.0
Match: 1pvvA_
Description: Refined Structure of Pyrococcus furiosus Ornithine Carbamoyltransferase at 1.87 A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ornithine carbamoyltransferase activity 6.08861672645671 bayes_pls_golite062009
carboxyl- or carbamoyltransferase activity 5.32518877756022 bayes_pls_golite062009
aspartate carbamoyltransferase activity 3.84118892938517 bayes_pls_golite062009
transferase activity 2.2887439598954 bayes_pls_golite062009
carbamoyl-phosphate synthase activity 2.21516900257798 bayes_pls_golite062009
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 2.19154218663721 bayes_pls_golite062009
catalytic activity 2.06069688716378 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 1.54712264845123 bayes_pls_golite062009
binding 1.00470116390248 bayes_pls_golite062009
dihydroorotase activity 0.585784960037124 bayes_pls_golite062009
protein binding 0.171217252293449 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle