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Protein Overview: YJL068C

General Information:
Name(s) found: YJL068C [SGD]
Description(s) found:
Found 37 descriptions.
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  • Non-essential intracellular esterase that can function as an S-formylglutathione hydrolase; may be involved in the detoxification of formaldehyde, which can be metabolized to S-formylglutathione; similar to human esterase D [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 299 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: formaldehyde catabolic process [IMPLink to PubMed article]
    Molecular Function: S-formylglutathione hydrolase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVVKEFSVC GGRLIKLSHN SNSTKTSMNV NIYLPKHYYA QDFPRNKRIP TVFYLSGLTC  60
   61 TPDNASEKAF WQFQADKYGF AIVFPDTSPR GDEVANDPEG SWDFGQGAGF YLNATQEPYA 120
  121 QHYQMYDYIH KELPQTLDSH FNKNGDVKLD FLDNVAITGH SMGGYGAICG YLKGYSGKRY 180
  181 KSCSAFAPIV NPSNVPWGQK AFKGYLGEEK AQWEAYDPCL LIKNIRHVGD DRILIHVGDS 240
  241 DPFLEEHLKP ELLLEAVKAT SWQDYVEIKK VHGFDHSYYF VSTFVPEHAE FHARNLGLI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ESC8 IOC2 IOC3 IOC4 ISW1 YJL068C
    View Details Ho Y, et al. (2002) CAT5 COR1 TAL1 YJL068C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YJL068C Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..299] PSI-BLAST 48.0 Antigen 85b

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • S-formylglutathione hydrolase activity
    		•  2.11404818814754 bayes_pls_golite062009
  • hydrolase activity
    		•  1.75934962198703 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.09488027320166 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle