YRC Public Data Repository - Protein Structure Prediction

Protein:	YJL068C
Organism:	Saccharomyces cerevisiae
Length:	299 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJL068C.

Description	E-value	Query Range	Subject Range
gi\|12846304 - gi\|12846304\|dbj\|BAB27115.1\| unnamed protein product [Mus musculus]	9.0E-77	[1..297]	[33..311]
ESTD_PIG - S-formylglutathione hydrolase OS=Sus scrofa GN=ESD PE=2 SV=1	8.0E-75	[1..297]	[3..281]
gi\|12654663, gi\|... - gi\|30582957\|gb\|AAP35708.1\| esterase 10 [Homo sapiens], gi\|217035508\|pdb\|3FCX\|B Chain B, Crystal Stru... gi\|60655501, gi\|... - gi\|60655501\|gb\|AAX32314.1\| esterase D/formylglutathione hydrolase [synthetic construct], gi\|60655499...	9.0E-75	[1..297]	[3..281]
gi\|11351274 - pir\|\|A83191 probable esterase PA3628 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|9949787, gi\|1... - gi\|9949787\|gb\|AAG07016.1\|AE004783_1 probable esterase [Pseudomonas aeruginosa PAO1], gi\|15598824\|ref...	2.0E-73	[1..297]	[5..282]
gi\|213052620 - gi\|213052620\|ref\|ZP_03345498.1\| putative esterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|213421237 - gi\|213421237\|ref\|ZP_03354303.1\| putative esterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|29141170, gi\|... - gi\|29141170\|ref\|NP_804512.1\| putative esterase [Salmonella enterica subsp. enterica serovar Typhi st... gi\|213424248 - gi\|213424248\|ref\|ZP_03357107.1\| putative esterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|16761136 - gi\|16761136\|ref\|NP_456753.1\| putative esterase [Salmonella enterica subsp. enterica serovar Typhi st... gi\|213646023 - gi\|213646023\|ref\|ZP_03376076.1\| putative esterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|214000075 - gi\|214000075\|ref\|ZP_03410810.1\| putative esterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|16503434, gi\|... - gi\|25321677\|pir\|\|AB0782 probable esterase STY2428 [imported] - Salmonella enterica subsp. enterica s...	9.0E-73	[1..296]	[1..276]
gi\|190409431 - gi\|190409431\|gb\|EDV12696.1\| hypothetical protein SCRG_03602 [Saccharomyces cerevisiae RM11-1a] YJL068C - Non-essential intracellular esterase that can function as an S-formylglutathione hydrolase; may be i... gi\|207343992 - gi\|207343992\|gb\|EDZ71277.1\| YJL068Cp-like protein [Saccharomyces cerevisiae AWRI1631] SFGH_YEAST - S-formylglutathione hydrolase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YJL068C PE...	3.0E-71	[1..299]	[1..299]
gi\|25321686 - pir\|\|AI2156 S-formylglutathione hydrolase [imported] - Nostoc sp. (strain PCC 7120) gi\|17230300, gi\|... - gi\|17230300\|ref\|NP_486848.1\| S-formylglutathione hydrolase [Nostoc sp. PCC 7120], gi\|17131901\|dbj\|BA...	2.0E-70	[1..298]	[4..281]
gi\|189355371, gi... - gi\|189355371\|gb\|EDU73790.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4401], gi... gi\|188015330, gi... - gi\|188015330\|gb\|EDU53452.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4113], gi... gi\|189362784, gi... - gi\|189362784\|gb\|EDU81203.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4486], gi... gi\|189366086, gi... - gi\|189366086\|gb\|EDU84502.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4501], gi... gi\|217327775, gi... - gi\|217327775\|ref\|ZP_03443858.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. TW14588... gi\|209400188, gi... - gi\|209400188\|ref\|YP_002271565.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4115... gi\|15832300, gi\|... - gi\|15832300\|ref\|NP_311073.1\| putative esterase [Escherichia coli O157:H7 str. Sakai], gi\|13362515\|db... gi\|75259626, gi\|... - gi\|75259626\|ref\|ZP_00730928.1\| COG0627: Predicted esterase [Escherichia coli E22], gi\|193062460\|ref\|... SFGH2_ECO57 - S-formylglutathione hydrolase YeiG OS=Escherichia coli O157:H7 GN=yeiG PE=3 SV=1 gi\|194427140, gi... - gi\|75211570\|ref\|ZP_00711649.1\| COG0627: Predicted esterase [Escherichia coli B171], gi\|194427140\|ref... gi\|209766214, gi... - pir\|\|H85853 probable esterase (EC 3.1.1.-) yeiG [imported] - Escherichia coli (strain O157:H7, subst... gi\|189001984, gi... - gi\|189001984\|gb\|EDU70970.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4076], gi... gi\|15802710, gi\|... - gi\|15802710\|ref\|NP_288737.1\| putative esterase [Escherichia coli O157:H7 EDL933], gi\|12516474\|gb\|AAG... gi\|187771284, gi... - gi\|187771284\|gb\|EDU35128.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4196], gi... gi\|189376613, gi... - gi\|189376613\|gb\|EDU95029.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC508], gi\|... gi\|189371323, gi... - gi\|189371323\|gb\|EDU89739.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC869], gi\|... gi\|208727411, gi... - gi\|208807610\|ref\|ZP_03249947.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4206]... gi\|195935533 - gi\|195935533\|ref\|ZP_03080915.1\| putative esterase [Escherichia coli O157:H7 str. EC4024] gi\|254794053, gi... - gi\|254794053\|ref\|YP_003078890.1\| predicted esterase [Escherichia coli O157:H7 str. TW14359], gi\|2545... gi\|208820764, gi... - gi\|208820764\|ref\|ZP_03261084.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4042]... gi\|208734049, gi... - gi\|208812772\|ref\|ZP_03254101.1\| S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4045]...	9.0E-70	[1..296]	[1..276]

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Predicted Domain #1

Region A:
Residues: [1-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVVKEFSVC GGRLIKLSHN SNSTKTSMNV NIYLPKHYYA QDFPRNKRIP TVFYLSGLTC  60
   61 TPDNASEKAF WQFQADKYGF AIVFPDTSPR GDEVANDPEG SWDFGQGAGF YLNATQEPYA 120
  121 QHYQMYDYIH KELPQTLDSH FNKNGDVKLD FLDNVAITGH SMGGYGAICG YLKGYSGKRY 180
  181 KSCSAFAPIV NPSNVPWGQK AFKGYLGEEK AQWEAYDPCL LIKNIRHVGD DRILIHVGDS 240
  241 DPFLEEHLKP ELLLEAVKAT SWQDYVEIKK VHGFDHSYYF VSTFVPEHAE FHARNLGLI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1f0nA_
Description:	Antigen 85b
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
S-formylglutathione hydrolase activity	2.11404818814754	bayes_pls_golite062009
hydrolase activity	1.75934962198703	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.09488027320166	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: