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Protein Overview: UBP7

General Information:
Name(s) found: UBP7 / YIL156W [SGD]
Description(s) found:
Found 21 descriptions.
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  • Ubiquitin-specific protease that cleaves ubiquitin-protein fusions [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1071 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ICLink to PubMed article]
    Biological Process: protein deubiquitination [TASLink to PubMed article]
    Molecular Function: ubiquitin-specific protease activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDDDKGTAM HPHITPFTPE YSNELLRRVQ DLYHEDIKHY YPQLKLEKLL DLLEHTEYLF  60
   61 ELYLDSIHHD RPNDALTAFI IGCYYVFLII PQSLQFQTRN KSYSIYTDLK KMYENEMNMT 120
  121 NVVLMVKKEI GVVLDESVKH GAGIEHRITK KRAFSVPADD LSGQVASLSL DTAAPQDHGL 180
  181 KGTFTEDDAE QSSPVWTAPN LEPNDQLKLA LLPEVIPTPA FREPERKTSV PVRPSVLLED 240
  241 VPSIYHEDDT SFASLNPPFR EITADRSVTH RKDSYHSVYM VDSGNLKEDN DDLFNVENDG 300
  301 FIQSLDILQK QSIITAPELF SILSNRVERE KVLLIDLRIP QRSAINHIVA PNLVNVDPNL 360
  361 LWDKQTNTPI YKDDILEHLL KENENFINRN KFDYIVYYTD VKTFMTINFD YAFIFFYLML 420
  421 TSQKTPLTTV PTTLLGGYEK WKKTLHSYAQ EYHISIEDYL YRPYSQKARL QQEQQQQQQQ 480
  481 PDSQDSFSAK ESSTKVPEPP SWKPPDLPIR LRKRPPPPPP VSMPTTPEIP PPLPPKIMVH 540
  541 SQVSSISRKP PIPAKQHVKK EQLNSNEIIQ RKRQHQHQHY DQQILQPQRA YNIPTIERSP 600
  601 NVYVSLSITG LRNLGNTCYI NSMIQCLFAA KTFRTLFISS KYKSYLQPIR SNGSHYSPKL 660
  661 SNSLSMLFNK MYLNGGCSVV PTGFLKVINQ LRPDLKIPDD QQDTQEFLMI LLDRLHDELS 720
  721 DQQHVANDYP NLLLYNADAL KVSNNEYKHW FDKNVIGNGI SPIDDIFQGQ MENSLQCKRC 780
  781 GYTTFNYSTF YVLSLAIPRR SMKLSKLGRS TEKRVKLEDC INMFTSDEVL SGENAWDCPR 840
  841 CGPTASVSTS VSALENEPSI VKSKKKKSRF FTLHTGTKRR HLDFFGDGIT EGHNSNNNNT 900
  901 TIFERERSRS PFRMLGGSGK RSSSSTPFST GGNDSNNSSD YKNKKLTTVK TINFVTLPKI 960
  961 LVIHLSRFYY DLTKKNNTVV TYPLILNIIL KNNDTMKYKL FGVVNHTGTL ISGHYTSLVN1020
 1021 KDLEHNVNIG RSKWYYFDDE VVKADRKHGS DKNLKISSSD VYVLFYERVY D

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BBC1 PPR1 SKT5 UBP7
    View Details Ho Y, et al. (2002) ECM29 GYP5 HOM6 PHO84 RVS167 UBI4 UBP7

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data UBP7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..222] MSA 1.002913 View MSA. No confident structure predictions are available.
    2 View Details [223..299] deduced N/A No confident structure predictions are available.
    3 View Details [300..478] Pfam 17.29243 Rhodanese-like domain No confident structure predictions are available.
    4 View Details [479..553] deduced N/A No confident structure predictions are available.
    5 View Details [554..648] Pfam 14.236572 No description for PF00442 was found. No confident structure predictions are available.
    6 View Details [649..981] MSA 4.236992 View MSA. No confident structure predictions are available.
    7 View Details [982..1071] Pfam 22.200659 Ubiquitin carboxyl-terminal hydrolase No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.660280721417663 bayes_pls_golite062009
  • protein binding
    		•  0.649203212147117 bayes_pls_golite062009
  • hydrolase activity
    		•  0.561937636673345 bayes_pls_golite062009
  • binding
    		•  0.524618154422454 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.514129714366787 bayes_pls_golite062009
  • transferase activity
    		•  0.24413644201982 bayes_pls_golite062009
  • phosphatase activity
    		•  0.0126182055752568 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle