Protein Overview: BET1

General Information:
Name(s) found:	BET1 / YIL004C [SGD]
Description(s) found: Found 27 descriptions. SHOW ALL	Type II membrane protein required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins [SGD]
Organism:	Saccharomyces cerevisiae
Length:	142 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IDA] ER to Golgi transport vesicle [IDA]
Biological Process:	ER to Golgi vesicle-mediated transport [IMP][IPI] retrograde vesicle-mediated transport, Golgi to ER [IDA]
Molecular Function:	receptor signaling protein serine/threonine kinase activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRFAGGNA YQRDTGRTQL FGPADGSNSL DDNVSSALGS TDKLDYSQST LASLESQSEE  60
   61 QMGAMGQRIK ALKSLSLKMG DEIRGSNQTI DQLGDTFHNT SVKLKRTFGN MMEMARRSGI 120
  121 SIKTWLIIFF MVGVLFFWVW IT

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		BET1 BOS1 GOS1 NYV1 SEC22 SNC1 SNC2 VTI1
View Details	Qiu et al. (2008)		BET1 BOS1 PEP12 SEC20 SEC22 SED5 SNC1 SNC2 YOS1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RAD6	BET1	1	Unpublished Fields Lab Data
View Screen	TOP3	BET1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	BET1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..59]	PSI-BLAST	17.522879	Syntaxin 1A N-terminal domain
2	View Details	[60..142]	PSI-BLAST	17.522879	Syntaxin 1A N-terminal domain

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2