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Protein Overview: YHR113W

General Information:
Name(s) found: YHR113W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Cytoplasmic aspartyl aminopeptidase; cleaves unblocked N-terminal acidic amino acid residues from peptide substrates; forms a 12 subunit homo-oligomeric complex; M18 metalloprotease family member; may interact with ribosomes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 490 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed articleLink to PubMed article]
    ribosome [IDALink to PubMed article]
    Biological Process: proteolysis [ISSLink to PubMed articleLink to PubMed article]
    Molecular Function: aspartyl aminopeptidase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRIQLRTMS SKTCKSDYPK EFVSFLNSSH SPYHTVHNIK KHLVSNGFKE LSERDSWAGH  60
   61 VAQKGKYFVT RNGSSIIAFA VGGKWEPGNP IAITGAHTDS PALRIKPISK RVSEKYLQVG 120
  121 VETYGGAIWH SWFDKDLGVA GRVFVKDAKT GKSIARLVDL NRPLLKIPTL AIHLDRDVNQ 180
  181 KFEFNRETQL LPIGGLQEDK TEAKTEKEIN NGEFTSIKTI VQRHHAELLG LIAKELAIDT 240
  241 IEDIEDFELI LYDHNASTLG GFNDEFVFSG RLDNLTSCFT SMHGLTLAAD TEIDRESGIR 300
  301 LMACFDHEEI GSSSAQGADS NFLPNILERL SILKGDGSDQ TKPLFHSAIL ETSAKSFFLS 360
  361 SDVAHAVHPN YANKYESQHK PLLGGGPVIK INANQRYMTN SPGLVLVKRL AEAAKVPLQL 420
  421 FVVANDSPCG STIGPILASK TGIRTLDLGN PVLSMHSIRE TGGSADLEFQ IKLFKEFFER 480
  481 YTSIESEIVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YHR113W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..490] Pfam 300.366532 Aminopeptidase I zinc metalloprotease (M18) No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle