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Protein Overview: SMI1

General Information:
Name(s) found: SMI1 / YGR229C [SGD]
Description(s) found:
Found 33 descriptions.
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  • Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 505 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cellular bud tip [TASLink to PubMed article]
    Biological Process: 1,3-beta-glucan biosynthetic process [TASLink to PubMed article]
    cellular cell wall organization [TASLink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLFKRKVKE WVYSLSTDDH YAEYNPDETP TFNMGKRLNS NNGQVNPSQM HLNSVDEEMS  60
   61 MGFQNGVPSN EDINIDEFTS TESNDGVSET LLAWRHIDFW TSEHNPDLNA TLSDPCTQND 120
  121 ITHAEEDLEV SFPNPVKASF KIHDGQEDLE SMTGTSGLFY GFQLMTLDQV VAMTQAWRNV 180
  181 AKNLNKRSQQ GLSHVTSTGS SSSMERLNGN KFKLPNIPDQ KSIPPNAVQP VYAHPAWIPL 240
  241 ITDNAGNHIG VDLAPGPNGK YAQIITFGRD FDTKFVIAEN WGEFLLSFAN DLEAGNWYLV 300
  301 DDNDDYFSGD GELVFRDKKS NGPIQDYFEV LKRRTWIKYQ ENLRSQQQKS QPDTSLQEQK 360
  361 YVPASQKKVA AEQPSTLNAE SIKGEDSGSA DVQSVQDHES VKIVKTEPSE AETTTVNTES 420
  421 LGQAEHEIKA DNVDIKQESE RKEDEKQPKV EEKEHVENEH VTESAKKDDD VNKQTEEMNK 480
  481 KEENEIRSDD AKVEEAREEF ENIAL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ANB1 ANR2 GPD2 HYP2 MEF1 MNP1 SMI1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SMI1 and CHC1 Huh WK, et al. (2003)
    View Data SMI1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..73] deduced N/A No confident structure predictions are available.
    2 View Details [74..318] FFAS03 1.95 No description for 2prvA was found.
    3 View Details [319..505] MSA 121.157997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle