Protein Overview: TDA10

General Information:
Name(s) found:	TDA10 / YGR205W [SGD]
Description(s) found: Found 34 descriptions. SHOW ALL	ATP-binding protein of unknown function; crystal structure resembles that of E.coli pantothenate kinase and other small kinases [SGD]
Organism:	Saccharomyces cerevisiae
Length:	290 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA ]
Biological Process:	biological_process [ND]
Molecular Function:	ATP binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDKSKTVLD YTIEFLDKYI PEWFETGNKC PLFIFFSGPQ GSGKSFTSIQ IYNHLMEKYG  60
   61 GEKSIGYASI DDFYLTHEDQ LKLNEQFKNN KLLQGRGLPG THDMKLLQEV LNTIFNNNEH 120
  121 PDQDTVVLPK YDKSQFKGEG DRCPTGQKIK LPVDIFILEG WFLGFNPILQ GIENNDLLTG 180
  181 DMVDVNAKLF FYSDLLWRNP EIKSLGIVFT TDNINNVYGW RLQQEHELIS KVGKGMTDEQ 240
  241 VHAFVDRYMP SYKLYLNDFV RSESLGSIAT LTLGIDSNRN VYSTKTRCIE

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		COP1 ECM29 PAA1 PTC3 REP1 TCB1 TDA10

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	SEC17	TDA10	1	Unpublished Fields Lab Data
View Screen	THG1	TDA10	1	Hazbun TR, et al. (2003)

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	TDA10	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..290]	PSI-BLAST	51.69897	Pantothenate kinase PanK

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
binding	1.26687146372087	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.420384345567397	bayes_pls_golite062009
pyrophosphatase activity	0.411077559082206	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.399864241228259	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.398496265411009	bayes_pls_golite062009
catalytic activity	0.234613562021476	bayes_pls_golite062009
hydrolase activity	0.216831145240405	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2