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Protein Overview: CUE3

General Information:
Name(s) found: CUE3 / YGL110C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 624 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRYNRVIE INGGNADISL PIVKFPPFKL RAQLIEKDPV VWLHLIETYV TYFEYLMQGA  60
   61 NVELLDESTL DHLRLFLRTY LHEIADEEGK LLSLGINHDV SEQLYLLKGW IFSLIKKCGL 120
  121 LHLQIFGDSL WNLIKVYVRR NPDSIRGLID GSLKPRINTQ RVQLDKSYQV QQHLKQLIES 180
  181 GKFKRIDLRC VEDLLSAKSM QPNKFAENFF TANWIEILEA LWAKGQGRGH KEARELIIIS 240
  241 LFSVSADRLL KITKELGISN FETLALYPLL GTMLINEGVH KRLPDLKSKL LFLNLGGLSM 300
  301 DEGDHMSYPT SSGTEVNEEQ LSALMELFPQ FSKYQLSQTL LAYDNNIELV TNKIFEDPTI 360
  361 IEAFSREPAE EEVEPVSDGD NASFTEELSI LDRGDSSKNK ELDKKIISEG VPDELRNKTL 420
  421 TRALKLLYEA DEDERDDTYD EADVNRSDPS KRIGLQEDEE SYDTKDDSNE VRQDHNYHIV 480
  481 EAYLWNLLKE DPKLFERSKR GTKVRKTMKE MTSWSDEKIE GWCRMLERSP TRARLLEKKF 540
  541 MFKGNSKTGK TSYVHNRDSQ NDGNVVKEQA KQKKSENIKK HEPQSTEQKK RQHAKNEKRK 600
  601 GARANHNRKK GHDKKLARAG NNAI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CUE3 YKR023W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CUE3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..314] deduced N/A No confident structure predictions are available.
    2 View Details [315..393] Pfam 11.49485 CUE domain No confident structure predictions are available.
    3 View Details [394..624] deduced N/A No confident structure predictions are available.
    4 View Details [448..624] MSA 2.017995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.34590276347208 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle