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View Structure Prediction Details

Protein: CUE3
Organism: Saccharomyces cerevisiae
Length: 624 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CUE3.

Description E-value Query
Range
Subject
Range
CUE3_YEAST - CUE domain-containing protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CUE3 PE=...
CUE3 - Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecu...
0.0 [1..624] [1..624]
CUE3_SCHPO - CUE domain-containing protein 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC1906.0...
SPCC1906.02c - CUE domain protein Cue3
0.0 [234..598] [184..581]

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Predicted Domain #1
Region A:
Residues: [1-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRYNRVIE INGGNADISL PIVKFPPFKL RAQLIEKDPV VWLHLIETYV TYFEYLMQGA  60
   61 NVELLDESTL DHLRLFLRTY LHEIADEEGK LLSLGINHDV SEQLYLLKGW IFSLIKKCGL 120
  121 LHLQIFGDSL WNLIKVYVRR NPDSIRGLID GSLKPRINTQ RVQLDKSYQV QQHLKQLIES 180
  181 GKFKRIDLRC VEDLLSAKSM QPNKFAENFF TANWIEILEA LWAKGQGRGH KEARELIIIS 240
  241 LFSVSADRLL KITKELGISN FETLALYPLL GTMLINEGVH KRLPDLKSKL LFLNLGGLSM 300
  301 DEGDHMSYPT SSGT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [315-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVNEEQLSAL MELFPQFSKY QLSQTLLAYD NNIELVTNKI FEDPTIIEAF SREPAEEEVE  60
   61 PVSDGDNASF TEELSILDR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 11.49485
Match: PF02845
Description: CUE domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [394-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDSSKNKELD KKIISEGVPD ELRNKTLTRA LKLLYEADED ERDDTYDEAD VNRSDPSKRI  60
   61 GLQEDEESYD TKDDSNEVRQ DHNYHIVEAY LWNLLKEDPK LFERSKRGTK VRKTMKEMTS 120
  121 WSDEKIEGWC RMLERSPTRA RLLEKKFMFK GNSKTGKTSY VHNRDSQNDG NVVKEQAKQK 180
  181 KSENIKKHEP QSTEQKKRQH AKNEKRKGAR ANHNRKKGHD KKLARAGNNA I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.34590276347208 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [448-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPSKRIGLQE DEESYDTKDD SNEVRQDHNY HIVEAYLWNL LKEDPKLFER SKRGTKVRKT  60
   61 MKEMTSWSDE KIEGWCRMLE RSPTRARLLE KKFMFKGNSK TGKTSYVHNR DSQNDGNVVK 120
  121 EQAKQKKSEN IKKHEPQSTE QKKRQHAKNE KRKGARANHN RKKGHDKKLA RAGNNAI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle