Protein Overview: USE1

General Information:
Name(s) found:	USE1 / YGL098W [SGD]
Description(s) found: Found 31 descriptions. SHOW ALL	Essential SNARE protein localized to the ER, involved in retrograde traffic from the Golgi to the ER; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	245 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA]
Biological Process:	ER to Golgi vesicle-mediated transport [IMP] retrograde vesicle-mediated transport, Golgi to ER [IGI][IMP]
Molecular Function:	SNAP receptor activity [IGI][IPI][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAETSNDPFL SYVLSSKQLT NLNRLRRKAV TKQLGSSDDN KVSEEFLRYQ HTYQREAFEY  60
   61 LQTKHDAHKI MESQYEQYQS SSKTRRYSID LDSVDAVDTE SQTEYPNEEF IDRNEDSEAV 120
  121 MELRKRLLGK GQNKGLGYET TKSVDRQIED QDTLQQDLIQ DMSKLVGSLK QGAVAFQSAL 180
  181 DEDKQVLGAA EIGIQVASQG LMDVSGKLRK YDKSKLSYLF YITVFIFMIL GLVFTFIIIQ 240
  241 LFPAL

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		DSL1 SEC22 SEC39 TIP20 USE1
View Details	Gavin AC, et al. (2006)		DSL1 SEC39 TIP20 UFE1 USE1
View Details	Qiu et al. (2008)		BOS1 SSO1 USE1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	THP2	USE1	2	Unpublished Fields Lab Data
View Screen	FRQ1	USE1	2	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	USE1	Huh WK, et al. (2003)
View Data	USE1 and ERG6	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..245]	Pcons	2.18	Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2