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Protein Overview: YBP2

General Information:
Name(s) found: YBP2 / YGL060W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Central kinetochore associated protein that mediates mitotic progression; interacts with several central kinetochore proteins and the centromeric histone Cse4p; role in resistance to oxidative stress; similarity to Ybp1p and Slk19p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 641 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYNEQVNSGK SIKEKERYLD ALLKILKDNP VTLKEIGWDL PKGLLQFFSR KNINVNIHLV  60
   61 FSPLVSSVME CFNELAINGN PKECLLTACE LVSTLHIVLT ETGDSDEENE DLNDSNRNDA 120
  121 SNITDELSVI TPEIGHYMAK NTVEFIPNLK IYVLFEFMSL LLKRVDTLYP SKFLAMVTSA 180
  181 IIKYVTTNVQ AMDDPHFILR IVYNFCTNYS PAQPSASLTD GISTNDLEKI HDDESALQKK 240
  241 LLANLSVFVI SNCLKNHPGN IDKIYFKTLM HKKTDENEID ASVLQICHQY YEYVTSLDVH 300
  301 MKELLEKCLV ESRSIYNSLL MNPAASTPEF KEEINQLVYE VSYAYQIKKL ADEKNLELDQ 360
  361 YGVVILSAIH YSKNGTHLLP QIDIQSAIYL YLRCTTASLF SEIYENKFLE SSVRYWLWVS 420
  421 TTETSTEKIK CALQELPGHI TTAFLQMLLM KTCNESNNDT KLTEITLLRR LLYLMPESTS 480
  481 FTFIFETLLH CPYITAKIAV LDILRDMMIR SPEAANRDET VGLIEQQNPG NTANSVPIMP 540
  541 TLPPRPYITI NEDRMASIHS IALICFSAAK QKKRTQGDLL LVLTYMKFFV SLRNKWDLGL 600
  601 LTLINKEISE SFQGEGEPEL AFINISNNTL GEYIEEMNIR S

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) MGE1 POR1 RVS161 RVS167 YBP2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 3912: TAP-tagged, strain background includes hpc2(delta) Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen HRT1 YBP2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YBP2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..50]
    [525..531]    		 ORFEUS 7.77 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
    2 View Details [51..101] ORFEUS 7.77 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
    3 View Details [102..293]
    [347..524]
    [532..641]    		 ORFEUS 7.77 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
    4 View Details [294..346] ORFEUS 7.77 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
    5 View Details [543..641] deduced N/A Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle